Gamma（γ）分析是剂量验证、剂量分布比较最重要的手段，由于不同剂量分布的坐标系定义/方向，基准点设置不一致，进行γ分析时往往要对待比较的剂量分布进行对齐，而目前常用的γ分析软件的对齐手段简单，在处理大照射野剂量分布时有显著错误，严重影响了剂量分析比较的准确性。二维剂量分布对齐的要求是在只进行平移、旋转等空间变换，从而达到两张剂量图上相应剂量点的空间位置一致。因为不同点之间的距离在对齐过程中必须是不变的，所以，本研究将对齐问题转化为刚性配准问题。本文采用基于归一化互相关的刚性配准方法，将治疗计划系统计算的剂量分布图与实际测量的剂量分布图进行配准，并输出配准后相应的平移量。选取36组计划系统和实测中心点一致的pinnacle³治疗计划系统设计的静态调强质量保证数据，其中，18组为小照射野，另18组为大照射野，使用PTW VeriSoft软件分别计算其在3%/3 mm、3%/2 mm、2%/2 mm通过标准下γ通过率。对于小照射野，直接计算与VeriSoft对齐后和刚性配准后的不同标准γ通过率结果均基本相当，其中在3%/3 mm通过标准下，VeriSoft对准后和刚性配准后与直接计算的γ通过率平均差异分别为0.5%和0.3%。对于大照射野，与直接计算的γ通过率结果相比，18组病例在VeriSoft对齐后于3%/3 mm、3%/2 mm、2%/2 mm通过标准下的γ通过率平均差异分别为17.1%、23.3%和28.3%，均呈现较大差异。而刚性配准后与直接计算在3%/3 mm、3%/2 mm和2%/2 mm标准下γ通过率的平均差异分别为0.4%、1.1%和2.3%，平均差异均较小。刚性配准解决了VeriSoft在处理大照射野剂量分布时存在显著错误的问题，其可以作为放射治疗计划剂量验证时一种适用于不同照射野剂量分布对齐的方法。

在自行搭建的双焦点太赫兹主动成像系统基础上，建立了与角度相关的拟合函数，并利用最小二乘拟合多项式的方法对拟合系数进行计算，成功将扫描轨迹的几何光学追迹计算过程简化成为二元函数计算。该系统为收发同路式像方旋转镜扫描。由于拟合自变量对太赫兹图像的影响很大，采用两种不同的拟合自变量进行计算，并且通过数值分析和成像结果分析比较两者的优劣。实验结果表明，当以旋转镜法向量的坐标分量作为拟合自变量时，计算扫描轨迹的速度减小至3 s/frame，且太赫兹图像非常准确。该系统实现了在约8 m处，50 cm×100 cm视场内达3 cm空间分辨率的快速精确成像。这为扫描式太赫兹快速成像系统提供了有价值的参考，对实时太赫兹安检、无损检测等领域有着实用意义。

We simulate the measurements of an active bifocal terahertz imaging system to reproduce the ability of the system to detect the internal structure of foams having embedded defects. Angular spectrum theory and geometric optics tracing are used to calculate the incident and received electric fields of the system and the scattered light distribution of the measured object. The finite-element method is also used to calculate the scattering light distribution of the measured object for comparison with the geometric optics model. The simulations are consistent with the measurements at the central axis of the horizontal stripe defects.

骨肉瘤是一种常见的恶性骨肿瘤, 常通过手术切除进行治疗。但术后造成的骨缺损难以自愈, 残余肿瘤细胞还会增加复发可能性。本研究开发了一种用于修复骨缺损和协同治疗骨肉瘤的掺钕介孔硼硅酸盐生物活性玻璃陶瓷骨水泥。首先通过溶胶-凝胶法结合固态反应制备了可作为光热剂和药物载体的掺钕介孔硼硅酸盐生物活性玻璃陶瓷微球(MBGC-xNd), 然后将微球与海藻酸钠(SA)溶液混合制备了可同时进行光热治疗和化学治疗的可注射骨水泥(MBGC-xNd/SA)。结果表明掺Nd³⁺赋予微球可控的光热性能, 负载阿霉素(DOX)的微球显示出持续的药物释放行为。此外, 载药骨水泥的药物释放量随着温度的升高而显著增加, 说明光热疗法产生的热量可促进DOX释放。体外细胞实验结果表明, MBGC-xNd/SA具有良好的促成骨活性, 并且光热-化学联合疗法对MG-63骨肉瘤细胞起到了更显著的杀伤作用, 表现出协同效应。因此，MBGC-xNd/SA作为一种新颖的多功能骨修复材料, 在骨肉瘤的术后治疗方面具有良好的应用前景。

In the quest to realize a scalable quantum network, semiconductor quantum dots (QDs) offer distinct advantages, including high single-photon efficiency and indistinguishability, high repetition rate (tens of gigahertz with Purcell enhancement), interconnectivity with spin qubits, and a scalable on-chip platform. However, in the past two decades, the visibility of quantum interference between independent QDs rarely went beyond the classical limit of 50%, and the distances were limited from a few meters to kilometers. Here, we report quantum interference between two single photons from independent QDs separated by a 302 km optical fiber. The single photons are generated from resonantly driven single QDs deterministically coupled to microcavities. Quantum frequency conversions are used to eliminate the QD inhomogeneity and shift the emission wavelength to the telecommunication band. The observed interference visibility is 0.67 ± 0.02 (0.93 ± 0.04) without (with) temporal filtering. Feasible improvements can further extend the distance to ∼600 km. Our work represents a key step to long-distance solid-state quantum networks.