目的: 依据低能量激光作用于尖牙的远中移动效果来评判低能量激光加速正畸牙齿移动的有效性。方法: 本次Meta分析步骤以PRISMA声明为依据, 应用计算机检索PubMed、Cochrane Library、Embase、CNKI、维普以及万方等数据库, 检索时间为2000年1月-2021年12月, 汇总所有随机对照试验, 应用RevMan5.3和STATE软件进行Meta分析。结果: 共纳入7篇研究, 累计224个样本量。Meta分析结果显示: 与对照组相比, 低能量激光组在治疗后7 d(WMD=0.360,95%CI=0.330~0.389,P＜0.05), 28 d (WMD=0.353,95%CI=0.141~0.566,P＜0.05), 60 d(WMD=0.301,95%CI=0.101~0.502,P＜0.05), 90 d(WMD=0.414,95%CI=0.179~0.650,P＜0.05)尖牙远中移动距离显著增加, 差异具有统计学意义。结论: 低能量激光作为正畸治疗辅助手段, 能有效促进正畸牙齿移动。

探讨激光心肌血运重建术(TMLR)联合血管内皮祖细胞(EPCs)移植治疗缺血性心脏病。将18只杂种犬成功建立急性心肌梗塞(AMI)动物模型后随机分为对照组，TMLR组和TMLR+EPCs组，每组6只。TMLR组：AMI后针对缺血区心肌进行激光打孔。TMLR+EPCs组：TMLR术后将EPCs与藻酸钙载体复合物移植入缺血区心肌激光孔道内。术后4周评价心功能和检测缺血区心肌组织新生血管状况。 结果表明，TMLR+EPCs组心肌局部收缩力明显高于对照组和TMLR组，心功能明显改善。TMLR+EPCs组激光孔道内有新生血管样结构生长，而TMLR组激光孔道内形成纤维化瘢痕。TMLR+EPCs组较TMLR组激光孔道周围新生血管计数明显增多，并且两组均较对照组明显增多。TMLR联合EPCs及载体复合物移植促进缺血心肌新生血管形成，增加心肌局部收缩力，改善心功能。

This is the first tomography-presentation of the optical properties of a normal canine prostate, in vivo, in its native intact environment in the pelvic canal. The imaging was performed by trans-rectal near-infrared (NIR) optical tomography in steady-state measurement at 840 nm on three sagittal planes across the right lobe, middle-line, and left lobe, respectively, of the prostate gland. The NIR imaging planes were position-correlated with concurrently applied trans-rectal ultrasound, albeit there was no spatial prior employed in the NIR tomography reconstruction. The reconstructed peak absorption coefficients of the prostate on the three planes were 0.014, 0.012, and 0.014mm?1. The peak reduced scattering coefficients were 5.28, 5.56, and 6.53mm?1. The peak effective attenuation coefficients were 0.45, 0.43, and 0.50mm?1. The absorption and effective attenuation coefficients were within the ranges predictable at 840nm by literature values which clustered sparsely from 355 nm to 1064 nm, none of which were performed on a canine prostate with similar conditions. The effective attenuation coefficients of the gland were shown to be generally higher in the internal aspects than in the peripheral aspects, which is consistent with the previous findings that the urethral regions were statistically more attenuating than the capsular regions.

目的:研究1064nm和532nm波长激光在激光能量为140mJ/pulse(脉冲)时对犬心肌切割效率.方法:用Q开关Nd:YAG 1064和532nm波长脉冲激光分别照射犬离体和在体心肌组织,光学显微镜和偏振光学显微镜行组织学分析,观察不同条件下激光切割组织的深度和光热对组织的损伤.结果:离体和在体实验,1064nm波长激光的切割效率高于532nm(p＜0.01).在体和离体实验显示1064nm激光能量和重复率相同时,所致的切割效率无明显差异(p＞0.05),血液对1064nm激光的切割效率影响较小.相反,在532nm时血液对其影响较大,相同的激光能量和重复率,离体实验切割效率高于在体(p＜0.01).1064nm激光所致的光热和机械损伤均轻于532nm激光.结论:在切割效率方面,1064nm激光比532nm更适用于TMLR.1064nm Q开关Nd:YAG激光可通过光导纤维传输,是TMLR的一个有潜力的激光源.