
Author Affiliations
Abstract
Key Laboratory of Light Field Manipulation and Information Acquisition, Ministry of Industry and Information Technology, and Shaanxi Key Laboratory of Optical Information Technology, School of Physical Science and Technology, Northwestern Polytechnical University, Xi’an 710129, China
The conversion-efficiency for second-harmonic (SH) in optical fibers is significantly limited by extremely weak second-order nonlinearity of fused silica, and pulse pump lasers with high peak power are widely employed. Here, we propose a simple strategy to efficiently realize the broadband and continuous wave (CW) pumped SH, by transferring a crystalline GaSe coating onto a microfiber with phase-matching diameter. In the experiment, high efficiency up to 0.08 %W-1mm-1 is reached for a C-band pump laser. The high enough efficiency not only guarantees SH at a single frequency pumped by a CW laser, but also multi-frequencies mixing supported by three CW light sources. Moreover, broadband SH spectrum is also achieved under the pump of a superluminescent light-emitting diode source with a 79.3 nm bandwidth. The proposed scheme provides a beneficial method to the enhancement of various nonlinear parameter processes, development of quasi-monochromatic or broadband CW light sources at new wavelength regions.
nonlinear optics second-harmonic generation continuous wave pump high efficiency multi-frequencies mixing broad spectra microfibers gallium selenide Opto-Electronic Advances
2023, 6(9): 230012

Author Affiliations
Abstract
1 State Key Laboratory of Optoelectronic Materials and Technologies, School of Physics, Sun Yat-sen University, Guangzhou 510275, China
2 State Key Laboratory for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics, School of Physics, Peking University, Beijing 100871, China
Microcavities constructed from materials with a second-order nonlinear coefficient have enabled efficient second-harmonic (SH) generation at a low power level. However, it is still technically challenging to realize double resonance with large nonlinear modal overlap in a microcavity. Here, we propose a design for a robust, tunable, and easy coupling double-resonance SH generation based on the combination of a newly developed fiber-based Fabry–Perot microcavity and a sandwich structure, whose numerical SH conversion efficiency is up to 3000% W-1. This proposal provides a feasible way to construct ultra-efficient nonlinear devices for generation of classical and quantum light sources.
microcavity double resonance second-harmonic generation Chinese Optics Letters
2023, 21(11): 111901
Author Affiliations
Abstract
1 Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou 350007, P. R. China
2 Department of Pathology, Fujian Medical University Union Hospital, Fuzhou 350001, P. R. China
3 Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350001, P. R. China
4 Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, P. R. China
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors arising in the digest tract. It brings a challenge to diagnosis because it is asymptomatic clinically. It is well known that tumor development is often accompanied by the changes in the morphology of collagen fibers. Nowadays, an emerging optical imaging technique, second-harmonic generation (SHG), can directly identify collagen fibers without staining due to its noncentrosymmetric properties. Therefore, in this study, we attempt to assess the feasibility of SHG imaging for detecting GISTs by monitoring the morphological changes of collagen fibers in tumor microenvironment. We found that collagen alterations occurred obviously in the GISTs by comparing with normal tissues, and furthermore, two morphological features from SHG images were extracted to quantitatively assess the morphological difference of collagen fibers between normal muscular layer and GISTs by means of automated image analysis. Quantitative analyses show a significant difference in the two collagen features. This study demonstrates the potential of SHG imaging as an adjunctive diagnostic tool for label-free identification of GISTs.
Multiphoton imaging two-photon excited fluorescence second-harmonic generation gastrointestinal stromal tumors Journal of Innovative Optical Health Sciences
2023, 16(5): 2350007
中国激光
2023, 50(17): 1714016

Author Affiliations
Abstract
1 Ultrafast Laser Laboratory, Key Laboratory of Opto-electronic Information Science and Technology of Ministry of Education, School of Precision Instruments and Opto-electronics Engineering, Tianjin University, Tianjin 300072, China
2 Science and Technology on Electro-Optical Information Security Control Laboratory, Tianjin 300308, China
As a newly discovered type of structured light, a spatiotemporal optical vortex (STOV), which is remarkable for its space–time spiral phase and transverse orbital angular momentum (OAM), has garnered substantial interest. Most previous studies have focused on the generation, characterization, and propagation of STOVs, but their nonlinear frequency conversion remains largely unexplored. Here, we experimentally demonstrate the generation of green and ultraviolet (UV) STOVs by frequency upconversion of a STOV carried near-infrared (NIR) pulse emitted by a high repetition rate Yb-doped fiber laser amplifier system. First, we verify that the topological charge of spatiotemporal OAM (ST-OAM) is doubled along with the optical frequency in the second-harmonic generation (SHG) process, which is visualized by the diffraction patterns of the STOVs in the fundamental and second-harmonic field. Second, the space–time characteristic of NIR STOV is successfully mapped to UV STOV by sum-frequency mixing STOV at 1037 nm and Gaussian beams in the green band. Furthermore, we observe the topological charges of the ST-OAM could be degraded owing to strong space–time coupling and complex spatiotemporal astigmatism of such beams. Our results not only deepen our understanding of nonlinear manipulation of ST-OAM spectra and the generation of STOVs at a new shorter wavelength, but also may promote new applications in both classical and quantum optics.
ultraviolet spatiotemporal optical vortex second-harmonic generation sum-frequency generation Chinese Optics Letters
2023, 21(8): 080004
中国激光
2023, 50(15): 1507102
Author Affiliations
Abstract
1 College of Physics and Optoelectronic Engineering, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Shenzhen University, Shenzhen 518060, Guangdong, P. R. China
2 Department of Bioengineering and COMSET, Clemson University, Clemson, SC 29634 USA
Structured illumination microscopy (SIM) is suitable for biological samples because of its relatively low-peak illumination intensity requirement and high imaging speed. The system resolution is affected by two typical detection modes: Point detection and area detection. However, a systematic analysis of the imaging performance of the different detection modes of the system has rarely been conducted. In this study, we compared laser point scanning point detection (PS-PD) and point scanning area detection (PS-AD) imaging in nonconfocal microscopy through theoretical analysis and simulated imaging. The results revealed that the imaging resolutions of PS-PD and PS-AD depend on excitation and emission point spread functions (PSFs), respectively. Especially, we combined the second harmonic generation (SHG) of point detection (P-SHG) and area detection (A-SHG) with SIM to realize a nonlinear SIM-imaging technique that improves the imaging resolution. Moreover, we analytically and experimentally compared the nonlinear SIM performance of P-SHG with that of A-SHG.
Super-resolution structured illumination microscopy second harmonic generation Journal of Innovative Optical Health Sciences
2023, 16(4): 2350010