中国激光医学杂志, 2008, 17 (2): 129, 网络出版: 2008-08-17  

膀胱癌的光动力学治疗

Photodynamic Therapy on Bladder Cancer
作者单位
上海交通大学医学院附属仁济医院泌尿外科,上海市,200001
摘要
光动力学疗法(photodynamic therapy,PDT)是一种新兴的治疗肿瘤的方法,近来被应用于膀胱肿瘤的治疗.笔者就PDT治疗膀胱癌的原理、基本技术、适应证及并发症、疗效及发展前景等做一综述.
Abstract
参考文献

[1] 董胜国.主编.膀胱肿瘤[M].北京:人民卫生出版社,2007,1-5.

[2] Dennis ED,Dai F,Rakesh KJ,et al.Photodynamic them-py for cancer[J].Nature Rev,2003,3:380-387.

[3] 许川山,吴士明,杨青,等.BPD-MA光动力作用对膀胱癌细胞凋亡及bcl-2蛋白表达的影响[J].应用激光,2005,25:204-206.

[4] Fotinos N,Campo MA,Popewycz F,et al.5-ALA deriva-tires in photomedicine:characteristics,application and per-spectives[J].Photochem Photobiol,2006,82:994-1015.

[5] Vancher L,Jichlinski P,Lange N,et al.Hexyl-aminole-vulinate-mediated photodynamic thempy:how to spare nor-mal urothehum.An in vitro approach[J].Lasers Surg Med,2007,39:67-75.

[6] Stavropoulos NE,Kim A,Nseyo UU.et al.Hypericum perforatum L.extract novel photosensitizer against human bladder cancer cells[J].J Photochem Photobiol B,2006,84:64-69.

[7] Hendrickx N,Dewaele M,Buytaert E,et al.Targeted in-hibition of p38alpha MAPK suppresses tumor associated en-dothelial cell migration in response to hypericin.based pho-todynamic therapy[J].Biochem Biophys Res Commun,2005,337:928-395.

[8] 郑景存,姜宁,王国增,等.国产新型光敏剂CDHS801光动力学疗法杀伤膀胱癌T24细胞效应的研究[J].中国激光医学杂志,2007,16:142-145.

[9] 米其武,曹正国,周四维,等.金属卟啉化合物的光动力学作用对人膀胱癌细胞增殖与凋亡的影响及其机制[J].中华实验外科杂志,2006,23:93-95.

[10] Riedl CR,Danihchendo D,Koenig F,et al.Fluores-cence endoscopy with 5-aminolevulinic acid reduces the early recurrence rate in bladder cancer[J].J Urol,200l,165:1121-1123.

[11] Pogue BW,Braun RD.Photodynamic therapy with verte-porfin in the radiation-induced fibrosarcoma-1 tumor cau-ses enhanced radiation sensitivity[J].Cancer Res,2003,63:1025-1033.

[12] Kamuhabwa AR,Huygens A,Roskams T,et al.Enhan-cing the photodynamic effect of hypericin in human blad-der transitional cell carcinoma sphemids by the use of the oxygen carrier,perfluorodeealin[J].Int J Oncol,2006,28:775-780.

[13] Iangmack K,Mehta R,Twyman P,et al.Topical photo-dynamic therapy at low fluence rates-theory and practice[J].J Photochem Photobiol B,2001,60:37-43.

[14] Shackley DC,Briggs C,Gilhooley A,et al.Photodynam-ic therapy for superficial bladder cancer under local an-aesthetic[J].BJU Int,2002,89:656-670.

[15] Van SH,Beck JF,Veflaan CW.et al.Comparison of normal piglet bladder damage after PDT with oral or intra-vesieal administration of ALA[J].Lasers Med Sci,2002,17:238-245.

[16] Wahlfors J,Talja M,Kosma VM,et al.The effect of photodynamic therapy on rat urinary bladder with ortho-topic urothelial carcinoma[J].BJU Int,2003,92:125-130.

[17] Manyak MJ,Ogan K.Photodynamlc therapy for refractory superficial bladder cancer:long term clinical outcomes of single treatment using intravesical diffusion medium[J].J Endourol,2003,17:633-639.

[18] Turchiello RF,Vena FC,Maillard P,et al.Cubic phase gel as a drug delivery system for topical application of 5-ALA,its ester derivatives and m-THPC in photodynamic therapy(PDT)[J].J Photochem Photobiol B:Biology,2003,70:1-6.

[19] Miron K,Miraslaw K,Asta J,et al.Biological activity of 5-aminolevulinic acid and its methyl ester after storage under different conditions[J].J Photochem Photobiol B:Biology,2007,87:67-72.

[20] Andreasp PB,Hannes S,Arnulf S,et al.Photodynamic therapy with intravesical instillation of 5-ALA for patients with recurrent superficial bladder cancer:a singer center study[J].Urology,2003,61:338-341.

[21] McClellan M,Walther MD.The role of photedynamic therapy in the treatment of recurrent superficial bladder cancer[J].Urol Clin North Am,2000,27:162-170.

[22] Nseyo UO,Shumaker B,Klein E,et al.Photodynamic therapy using porfimer sodium as an alternative to cystec-tomy in patients with refractory transitional cell carcinoma in situ of the bladder[J].J Urol,1998,160:39-44.

[23] Schaffer M,Schaffer PM.Application of Photofrin as a specific radiosensitizer agent in patients with bladder cancer-a report of two patients[J].Photochem Photobiol Sei,2002,1:686-689.

[24] Christian L,Ruth K,Guenther B,et al.Combined che-motherapeutic and photodynamic treatment on human bladder cells by hematoporphyrin-platinum(Ⅱ)conju-gates[J].Cancer Lett,2004,203:171-180.

[25] French AJ,Datta SN,Allman B,et al.Investigation of sequential mitomycin C and photodynamic therapy in a mi-tomycin-resistant bladder cancer cell-line model[J].BJU Int,2004,93:156-161.

陈伟, 薄隽杰. 膀胱癌的光动力学治疗[J]. 中国激光医学杂志, 2008, 17(2): 129. 陈伟, 薄隽杰. Photodynamic Therapy on Bladder Cancer[J]. Chinese Journal of Laser Medicine & Surgery, 2008, 17(2): 129.

关于本站 Cookie 的使用提示

中国光学期刊网使用基于 cookie 的技术来更好地为您提供各项服务,点击此处了解我们的隐私策略。 如您需继续使用本网站,请您授权我们使用本地 cookie 来保存部分信息。
全站搜索
您最值得信赖的光电行业旗舰网络服务平台!