Analysis of opto-thermal interaction of porcine stomach tissue with 808-nm laser for endoscopic submucosal dissection

Seongjun Kim; M. Tamim Hossain; Don Haeng Lee; Jung Kyung Kim

doi:doi:10.1142/s1793545815500431

Journal of Innovative Optical Health Sciences, 2015, 8 (6): 1550043, Published Online: Jan. 10, 2019

Analysis of opto-thermal interaction of porcine stomach tissue with 808-nm laser for endoscopic submucosal dissection

论文大纲

Seongjun Kim ¹M. Tamim Hossain ²Don Haeng Lee ³Jung Kyung Kim ^4,*

Author Affiliations

¹ Department of Mechanical Engineering Graduate School, Kookmin University Seoul 136-702, Republic of Korea

² Department of Integrative Biomedical Science and Engineering, Graduate School, Kookmin University Seoul 136-702, Republic of Korea

³ Division of Gastroenterology Department of Internal Medicine Inha University School of Medicine National Center of E±cacy Evaluation for the Development of Health Products Targeting Digestive Disorders Utah-Inha DDS & Advanced Therapeutics Research Center 27 Inhang-ro, Jung-gu, Incheon 400-711, Republic of Korea

⁴ Department of Mechanical Engineering Kookmin University Seoul 136-702, Republic of Korea

Near-infrared laser surgical intervention laser-tissue interaction submucosal fluid cushion temperature distribution

Abstract

In endoscopic submucosal dissection (ESD), the narrow gastrointestinal space can cause difficulty in surgical interventions. Tissue ablation apparatuses with high-power CO₂ lasers or Nd:YAG lasers have been developed to facilitate endoscopic surgical procedures. We studied the interaction of 808-nm laser light with a porcine stomach tissue, with the aim of developing a therapeutic medical device that can remove lesions at the gastrointestinal wall by irradiating a near-infrared laser light incorporated in an endoscopic system. The perforation depths at the porcine fillet and the stomach tissues linearly increased in the range of 2–8mm in proportion to the laser energy density of 63.7–382 kJ/cm². Despite the distinct structural and compositional difference, the variation of the perforation depth between the stomach and the fillet was not found at 808-nm wavelength in our measurement. We further studied the laser–tissue interaction by changing the concentration of the methyl blue solution used conventionally as a submucosal fluidic cushion (SFC) in ESD procedures. The temperature of the mucosal layer increased more rapidly at higher concentration of the methyl blue solution, because of enhanced light absorption at the SFC layer. The insertion of the SFC would protect the muscle layer from thermal damage. We confirmed that more effective laser treatment should be enabled by tuning the opto-thermal properties of the SFC. This study can contribute to the optimization of the driving parameters for laser incision techniques as an alternative to conventional surgical interventions.

References

[1] S. J. Park, "Possibility of endoscopic surgery," Kor. J. Intern. Med. 79, 455–458 (2010).

[2] D. S. Han, "Gastrointestinal endoscopic surgery," Hanyang Med. Rev. 29(2), 75–82 (2008).

[3] M. Karita, M. Tada, K. Okita, "The successive strip biopsy partial resection technique for large early gastric and colon cancers," Gastrointest. Endosc. 38(2), 174–178 (1992).

[4] J. T. Au, A. Mittra, J. Wong, S. Carpenter, J. Carson, D. Haddad, S. Monette, P. Ezell, S. Patel, Y. Fong, "Flexible CO2 laser and submucosal gel injection for safe endoluminal resection in the intestines," Surg. Endosc. 26(1), 47–52 (2012).

[5] S. E. Fisher, J. W. Frame, R. M. Browne, R. M. Tranter, "A comparative histological study of wound healing following CO2 laser and conventional surgical excision of canine buccal mucosa," Arch. Oral Biol. 28(4), 287–291 (1983).

[6] J. R. Tuffin, J. A. Carruth, "The carbon dioxide surgical laser," Br. Dent. J. 149(9), 255–258 (1980).

[7] J.-H. Cho, J. Y. Cho, M.-Y. Kim, S. R. Jeon, T. H. Lee, H. G. Kim, S. Y. Jin, S. J. Hong, "Endoscopic submucosal dissection using a thulium laser: Preliminary results of a new method for treatment of gastric epithelial neoplasia," Endoscopy 45(9), 725–728 (2013).

[8] J. I. Youn, J. D. Holcomb, "Ablation efficiency and relative thermal confinement measurements using wavelengths 1,064, 1,320, and 1,444 nm for laserassisted lipolysis," Lasers Med. Sci. 28(2), 519–527 (2013).

[9] J. Cho, H. Byun, S. Lee, J. K. Kim, "Temperature distribution in deep tissue phantom during laser irradiation at 1,064 nm measured by thermocouples and thermal imaging technique," J. Vis. 14(3), 265– 272 (2011).

[10] M. N. Lee, S. H. Lee, C. C. Kim, "Clinical application of argon laser in pediatric dentistry," J. Kor. Acad. Pediatr. Dent. 24(1), 139–147 (1997).

[11] M. Fujishiro, N. Yahagi, K. Kashimura, Y. Mizushima, M. Oka, S. Enomoto, N. Kakushima, K. Kobayashi, T. Hashimoto, M. Iguchi, Y. Shimizu, M. Ichinose, M. Omata, "Comparison of various submucosal injection solutions for maintaining mucosal elevation during endoscopic mucosal resection," Endoscopy 36(7), 579–583 (2004).

[12] H. Yamamoto, H. Kawata, K. Sunada, K. Satoh, Y. Kaneco, K. Ido, K. Sugano, "Success rate of curative endoscopic mucosal resection with circumferential mucosal incision assisted by submucosal injection of sodium hyaluronate," Gastrointest. Endosc. 56, 507–512 (2002).

[13] T. Uraoka, T. Fujii, Y. Saito, T. Sumiyoshi, F. Emura, P. Bhandari, T. Matsuda, K. Fu, D. Saito, "Effectiveness of glycerol as a submucosal injection for EMR," Gastrointest. Endosc. 61, 736–740 (2000).

[14] A. B. Feitoza, C. J. Gostout, L. J. Burgart, A. Burkert, L. J. Herman, E. Rajan, "Hydroxypropyl methylcellulose: A better submucosal fluid cushion for endoscopic mucosal resection," Gastrointest. Endosc. 57, 41–47 (2003).

[15] I. Kumano, M. Ishihara, S. Nakamura, S. Kishimoto, M. Fujita, H. Hattori, T. Horio, Y. Tanaka, K. Hase, T. Maehara, "Endoscopic submucosal dissection for pig esophagus by using photocrosslinkable chitosan hydrogel as submucosal fluid cushion," Gastrointest. Endosc. 75(4), 841–848 (2012).

[16] M. Mital, E. P. Scott, "Thermal detection of embedded tumors using infrared imaging," J. Biomech. Eng. 129(1), 33–39 (2007).

[17] H. W. Kang, J. Kim, J. Oh, "Effect of wavelength on laser-assisted surgical techniques," Opt. Laser. Eng. 51(2), 104–110 (2013).

[18] D. E. Hudson, D. O. Hudson, J. M. Wininger, B. D. Richardson, "Penetration of laser light at 808 and 980 nm in bovine tissue samples," Photomed. Laser Surg. 31(4), 163–169 (2013).

[19] D. Obata, Y. Morita, R. Kawaguchi, K. Ishii, H. Hazama, K. Awazu, H. Kutsumi, T. Azuma, "Endoscopic submucosal dissection using a carbon dioxide laser with submucosally injected laser absorber solution (porcine model)," Surg. Endosc. 27(11), 4241–4249 (2013).

Seongjun Kim , M. Tamim Hossain , Don Haeng Lee , Jung Kyung Kim . Analysis of opto-thermal interaction of porcine stomach tissue with 808-nm laser for endoscopic submucosal dissection[J]. Journal of Innovative Optical Health Sciences, 2015, 8(6): 1550043.

Analysis of opto-thermal interaction of porcine stomach tissue with 808-nm laser for endoscopic submucosal dissection

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