[1] P. J. Fay, “Factor VIII structure and function," Int. J. Hematol. 83, 103–108 (2006)

[2] G. A. Vehar, B. Keyt, D. Eaton, H. Rodriguez, D. P. O'Brien, F. Rotblat, H. Oppermann, R. Keck, W. I. Wood, R. N. Harkins, E. G. Tuddenham, R. M. Lawn, D. J. Capon, “Structure of human factor VIII," Nature 312, 337–342 (1984)

[3] P. J. Fay, “Activation of factor VIII and mechanisms of cofactor action," Blood Rev. 18, 1–15 (2004)

[4] P. M. Mannucci, M. E. Mancuso, E. Santagostino, “How we choose factor VIII to treat hemophilia," Blood 119, 4108–4114 (2012)

[5] T. Burnouf, “Modern plasma fractionation," Transfus. Med. Rev. 21, 101–117 (2007)

[6] M. J. Maltesen, M. van de Weert, “Drying methods for protein pharmaceuticals," Drug Discov. Today Technol. 5, e81–e88 (2008)

[7] A. Kauppinen, M. Toiviainen, O. Korhonen, J. Aaltonen, K. Jarvinen, J. Paaso, M. Juuti, J. Ketolainen, “In-line multipoint near-infrared spectroscopy for moisture content quantiˉcation during freeze-drying," Anal. Chem. 85, 2377–2384 (2013)

[8] A. Kauppinen, M. Toiviainen, M. Lehtonen, K. Jarvinen, J. Paaso, M. Juuti, J. Ketolainen, “Validation of a multipoint near-infrared spectroscopy method for in-line moisture content analysis during freeze-drying," J. Pharm. Biomed. Anal. 95, 229–237 (2014)

[9] Committee SP, Pharmacopoeia of the People's Republic of China, People's Medical Publishing House, Beijing (2010)

[10] M. J. Pikal, “Freeze-drying of proteins: Process, formulation and stability," ACS Symp. Ser. 567, 120–133 (1994)

[11] L. L. Chang, D. Shepherd, J. Sun, X. C. Tang, M. J. Pikal, “Effect of sorbitol and residual moisture on the stability of lyophilized antibodies: Implications for the mechanism of protein stabilization in the solid state," J. Pharm. Sci. 94, 1445–1455 (2005)

[12] C. A. De Caro, A. Aichert, C. M. Walter, “Efficient, precise and fast water determination by the Karl Fischer titration," Food Control 12, 431–436 (2001)

[13] M. M. Pojic, J. S. Mastilovic, “Near infrared spectroscopy- advanced analytical tool in wheat breeding, trade, and processing," Food Bioprocess Technol. 6, 330–352 (2013)

[14] S. A. Haughey, S. F. Graham, E. Cancouet, C. T. Elliott, “The application of near-infrared re°ectance spectroscopy (NIRS) to detect melamine adulteration of soya bean meal," Food Chem. 136, 1557– 1561 (2013)

[15] M. Blanco, S. Maspoch, I. Villarroya, X. Peralta, J. M. Gonzalez, J. Torres, “Geographical origin classiˉcation of petroleum crudes from near-infrared spectra of bitumens," Appl. Spectrosc. 55, 834–839 (2001)

[16] H. C. Zang, J. F. Wang, L. Li, H. Zhang, W. Jiang, F. S. Wang, “Application of near-infrared spectroscopy combined with multivariate analysis in monitoring of crude heparin puriˉcation process," Spectrochim. Acta A Mol. Biomol. Spectrosc. 109, 8–13 (2013)

[17] W. Momose, K. Imai, S. Yokota, E. Yonemochi, K. Terada, “Process analytical technology applied for end-point detection of pharmaceutical blending by combining two calibration-free methods: Simultaneously monitoring specific near-infrared peak intensity and moving block standard deviation," Powder Technol. 210, 122–131 (2011)

[18] R. Kona, H. Qu, R. Mattes, B. Jancsik, R. M. Fahmy, S. W. Hoag, “Application of in-line near infrared spectroscopy and multivariate batch modeling for process monitoring in °uid bed granulation," Int. J. Pharm. 452, 63–72 (2013)

[19] A. Peinado, J. Hammond, A. Scott, “Development, validation and transfer of a near infrared method to determine in-line the end point of a fluidised drying process for commercial production batches of an approved oral solid dose pharmaceutical product," J. Pharm. Biomed. Anal. 54, 13–20 (2011)

[20] J. D. Perez-Ramos, W. P. Findlay, G. Peck, K. R. Morris, “Quantitative analysis of film coating in a pan coater based on in-line sensor measurements," AAPS Pharm. Sci. Tech 6, E127–136 (2005)

[21] P. Wang, H. Zhang, H. Yang, L. Nie, H. Zang, “Rapid determination of major bioactive iso- flavonoid compounds during the extraction process of kudzu (Pueraria lobata) by near-infrared transmission spectroscopy," Spectrochim. Acta. A Mol. Biomol. Spectrosc. 137, 1403–1408 (2015)

[22] J. Luypaert, D. L. Massart, Y. Vander Heyden, “Near-infrared spectroscopy applications in pharmaceutical analysis," Talanta 72, 865–883 (2007)

[23] M. Brulls, S. Folestad, A. Sparen, A. Rasmuson, “In-situ near-infrared spectroscopy monitoring of the lyophilization process," Pharm. Res. 20, 494– 499 (2003)

[24] V. Centner, D. L. Massart, O. E. de Noord, S. de Jong, B. M. Vandeginste, C. Sterna, “Elimination of uninformative variables for multivariate calibration," Anal. Chem. 68, 3851–3858 (1996)

[25] L. Norgaard, A. Saudland, J. Wagner, J. P. Nielsen, L. Munck, S. B. Engelsen, “Interval partial leastsquares regression (iPLS): A comparative chemometric study with an example from near-infrared spectroscopy," Appl. Spectrosc. 54, 413–419 (2000)

[26] H. D. Li, Y. Z. Liang, Q. S. Xu, D. S. Cao, “Key wavelengths screening using competitive adaptive reweighted sampling method for multivariate calibration," Anal. Chim. Acta. 648, 77–84 (2009)

[27] R. K. H. Galvao, M. C. U. Araujo, G. E. Jose, M. J. C. Pontes, E. C. Silva, T. C. B. Saldanha, “A method for calibration and validation subset partitioning," Talanta 67, 736–740 (2005)

[28] R. A. Davis, A. J. Charlton, S. Oehlschlager, J. C. Wilson, “Novel feature selection method for genetic programming using metabolomic 1H NMR data," Chemometr. Intell. Lab. 81, 50–59 (2006)

[29] Z. G. Song, P. X. Ling, H. C. Zang, L. Li, J. F. Wang, Y. Jin, H. R. Shao, X. Q. Zhu, F. Liu, F. S. Wang, “Development, validation and influence factor analysis of a near-infrared method for the molecular weight determination of xanthan gum," Carbohyd. Polym. 115, 582–588 (2015).