中国激光, 2021, 48 (15): 1507002, 网络出版: 2021-08-05
智能化精准光学诊疗技术研究进展 
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Research Progress in Intelligent and Precise Optical Diagnosis and Treatment Technology
图 & 表
图 1. 智能化精准光学诊疗技术的简述及其典型组成部分
Fig. 1. Overview of intelligent precision optical theranostics technology and its typical components
图 2. 光学成像与诊断技术原理图。(a)光与组织的典型相互作用;(b)不同波段的光学成像技术
Fig. 2. Schematic of optical imaging and diagnosis technology. (a) Representative light-tissue interactions; (b) optical imaging modalities at different wavelength ranges
图 3. 用于神经外科肿瘤的荧光光谱-光相干断层成像双模态光学精准诊断方法[20]
Fig. 3. Flowchart of the dual-modality optical method using fluorescence spectroscopy and OCT for precision diagnosis of tumors in neurosurgery[20]
图 5. 自动化激光扫描消融治疗设备与治疗效果图[65]。(a)设备结构示意图;(b)实物图;(c)~(e)分别为脑组织消融场景图、结果图
Fig. 5. Automatic laser scanning ablation system and laser ablation results[65]. (a) System configuration; (b) manufactured laser scanning ablation device; (c)--(e) brain tissue ablation experiment and laser ablation results
图 6. 智能化精准光学微创诊疗平台的发展
Fig. 6. The development of intelligent precision optical minimally invasive diagnosis and therapy platform
图 7. 扫描范围扩大化的激光消融系统。(a)基于MEMS振镜结构[123];(b)基于连续体结构控制[119];(c)基于气动柔性机器人结构[120]
Fig. 7. Laser ablation system with expanded scanning range. (a) Based on MEMS galvanometer structure[123]; (b) based on continuum structure[119]; (c) based on pneumatic flexible robot structure[120]
图 8. 集成荧光诊断与激光治疗的诊疗一体化系统。(a) 5-ALA诱导PpIX荧光引导激光消融系统的示意图;(b)在体激光消融试验;(c)脑组织消融治疗结果图[125]
Fig. 8. Theranostic system integrating fluorescence-based diagnosis and laser therapy. (a) System configuration of laser ablation treatment guided by 5-ALA-induced PpIX fluorecence; (b) in vivo laser ablation experiment; (c) laser ablation results on brain tissue[125]
李阳曦, 胡成全, 马龙飞, 张欣然, 廖洪恩. 智能化精准光学诊疗技术研究进展[J]. 中国激光, 2021, 48(15): 1507002. Yangxi Li, Chengquan Hu, Longfei Ma, Xinran Zhang, Hongen Liao. Research Progress in Intelligent and Precise Optical Diagnosis and Treatment Technology[J]. Chinese Journal of Lasers, 2021, 48(15): 1507002.
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