生物细胞亚显微结构对光散射特性的影响

孙杜娟; 胡以华; 王勇; 李乐; 李磊

doi:doi:10.3788/gzxb20134206.0710

光子学报, 2013, 42 (6): 710, 网络出版: 2013-06-14

生物细胞亚显微结构对光散射特性的影响

Sub-microstructures′ Influences on Cell′s Scattering Prosperities

论文大纲

孙杜娟 ^*胡以华王勇李乐李磊

作者单位

脉冲功率激光技术国家重点实验室(电子工程学院), 电子制约技术安徽省重点实验室, 合肥 230037

光散射细胞散射特性细胞亚显微结构时域有限差分方法 Light scattering Scattering property of cell Sub-microstructures Finite-difference time-domain (FDTD) method

摘要

构建细胞模型、“细胞基质”模型以及“细胞基质-细胞核”模型等3个模型, 分别表征不同层次细胞结构, 采用时域有限差分方法进行仿真计算, 分别比较了3个模型的远场雷达散射截面在5个散射区的数值差异, 分析了细胞器、细胞核和细胞基质等细胞亚显微结构对细胞电磁散射特性的影响.研究结果表明,生物细胞整体电磁散射特性主要由其细胞基质决定, 细胞核的存在显著增强了细胞在20°≤θ≤40°和150°≤θ≤180°两个散射区的散射能力, 随机分布的细胞器增强了细胞的侧向散射, 削弱了细胞核在上述两个散射区的散射效果, 使细胞散射波分布趋于均匀.

Abstract

A cell model, a cellularstroma model and a “cellularstroma & nuclear” model are presented, which demonstrate three types of biological cells, respectively. By using a FDTD method, models′ RCS in the far-field are compared, and influences of cell′s sub-microstructures, including organelles, nucleolus and cellularstroma on its scattering properties are researched. The results show that cells′ scattering properties are mainly determined by cellularstroma. Light scattering from cells and propagating in two directions of 20°≤θ≤40° and 150°≤θ≤180° are increased by nucleus but decreased by organelles, which distribute randomly, that making scattering light intensity in all direction more uniform.

参考文献

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孙杜娟, 胡以华, 王勇, 李乐, 李磊. 生物细胞亚显微结构对光散射特性的影响[J]. 光子学报, 2013, 42(6): 710. SUN Du-juan, HU Yi-hua, WANG Yong, LI Le, LI Lei. Sub-microstructures′ Influences on Cell′s Scattering Prosperities[J]. ACTA PHOTONICA SINICA, 2013, 42(6): 710.

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