提出一种基于单相机的偏振谱域光学相干层析方法。该方法基于全单模光纤光路，使用宽带光源实现微米纵向高分辨率成像性能。通过硬件和软件两方面对系统色散进行矫正补偿，提高系统的实际分辨率。为实现样本偏振态的测量，入射至样品表面及参考臂的光偏振态由偏振片和四个偏振控制器进行调制。此外，利用偏振片在不同时间的通道切换实现两正交通道光谱信号的分时探测。根据得到的正交光谱信息，计算重构样品强度图和相位延迟图。该系统成功实现了单相机的偏振OCT测量，通过获取离体生物组织的强度图和相位延迟图验证了系统的成像能力。该方法为实现小型化在体高分辨偏振成像打下基础。

In this Letter, we present B-scan-sectioned dynamic micro-optical coherence tomography (BD-MOCT) for high-quality sub-cellular dynamic contrast imaging. Dynamic micro-optical coherence tomography (D-MOCT) is a functional optical coherence tomography (OCT) technique performed on high-resolution (micron level) OCT systems; hundreds of consecutive B-scans need to be acquired for dynamic signal extraction, which requires relatively long data acquisition time. Bulk motions occurring during data acquisition (even at the micron level) may degrade the quality of the obtained dynamic contrast images. In BD-MOCT, each full B-scan is divided into several sub-B-scans, and each sub-B-scan repeats multiple times before the sample beam moves to the next sub-B-scan. After all of the sub-B-scans for a full B-scan are completely acquired, we stitch all of the sub-B-scans into the same number of full B-scans. In this way, the time interval between two consecutive stitched B-scans could be reduced multiple times for bulk-motion suppression. The performed scanning protocol modulates the scanning sequences of fast scanning and repeat scanning for improving the dynamic contrast image quality, while the total data acquisition time remains almost the same.

报道了一种基于偏振敏感光学相干层析术的人体组织退偏特性在体测量方法。以人体手指指甲为样品，采用基于斯托克斯矢量的测量方法和基于宏观穆勒矩阵的测量方法，获得了指甲的不同退偏参数图像，并通过比较图像来衡量这两种方法的优劣。基于穆勒矩阵的方法获得的图像中，能明显区分出甲床结构，对比度高，但能显示出的结构较少。基于斯托克斯矢量的方法获得的图像中，不同偏振光在样品同一位置处获得的退偏均匀度值不同。选取45°偏振光计算其后向反射光的圆偏振度可以获得样品结构信息，包括指甲的甲板、甲床和甲基质下的真皮层。基于斯托克斯矢量法入射45°偏振光测量圆偏振度的方法计算量小，且提取出的结构信息最多，成像效果最好。