Author Affiliations
Abstract
1 Department of Electronic Engineering Faculty of Electrical and Electronic Engineering University Tun Hussein Onn Malaysia Batu Pahat 86400, Johor, Malaysia
2 Department of Communication Engineering Faculty of Electrical and Electronic Engineering University Tun Hussein Onn Malaysia Batu Pahat 86400, Johor, Malaysia
Accepted 6 December 2013 Published 5 February 2014 This work presents the use of extended Modified Lambert Beer (MLB) model for accurate and continuous monitoring of percent blood carboxyhemoglobin (COHb) (SCO) and oxyhemoglobin (OxyHb) saturation (SO2) via a fitting procedure. This quantification technique is based on the absorption characteristics of hemoglobin derivatives in the wavelength range of 520–600 nm to give the best estimates of the required parameters. A comparison of the performance of the developed model and MLB law is made using attenuation data from Monte Carlo simulations for a two-layered skin model. The results revealed a lower mean absolute error of 0:4% in the values estimated by the developed model as compared to 10% that is given by the MLB law. This study showed that the discussed approach is able to provide consistent and accurate measurement of blood SO2 and SCO across different skin pigmentations suggesting that it may potentially be used as an alternative means for clinical diagnosis of carbon monoxide (CO) poisoning.
Blood carboxyhemoglobin saturation carbon monoxide poisoning blood oxyhemoglobin saturation modified Lambert Beer law Journal of Innovative Optical Health Sciences
2014, 7(3): 1450026