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Simultaneous blood flow and oxygenation measurements using an off-the-shelf spectrometer

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Abstract

Blood oxygenation and flow are both important parameters in a living body. In this Letter, we introduce a simple configuration to simultaneously measure blood flow and oxygenation using an off-the-shelf spectrometer. With the integration time of 10 ms, flow phantom measurements, a liquid blood phantom test, and an arm cuff occlusion paradigm were performed to validate the feasibility of the system. We expect this proof-of-concept study would be widely adopted by other researchers for acquiring both blood flow and oxygenation changes due to its straightforward configuration and the possibility of multimodal measurement.

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DOI:10.3788/col201816.071701

所属栏目:Medical optics and biotechnology

基金项目:This work was partially supported by the SGER grant NRF-2015R1D1A1A02062382 (J. G. Kim) and Global Ph.D. Fellowship Program NRF-2015H1A2A1032268 (M. Seong) through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, and GIST Research Institute in 2018. We declare that there is no conflict of interest to disclose.

收稿日期:2018-04-18

录用日期:2018-05-21

网络出版日期:2018-07-02

作者单位    点击查看

Myeongsu Seong:Department of Biomedical Science and Engineering, Institute of Integrated Technology, Gwangju Institute of Science and Technology, Gwangju 61005, Korea
Phuong Minh Mai:School of Electrical Engineering and Computer Science, Gwangju Institute of Science and Technology, Gwangju 61005, Korea
Kijoon Lee:School of Undergraduate Studies, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, Korea
Jae Gwan Kim:Department of Biomedical Science and Engineering, Institute of Integrated Technology, Gwangju Institute of Science and Technology, Gwangju 61005, KoreaSchool of Electrical Engineering and Computer Science, Gwangju Institute of Science and Technology, Gwangju 61005, Korea

联系人作者:Jae Gwan Kim(jaekim@gist.ac.kr)

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引用该论文

Myeongsu Seong, Phuong Minh Mai, Kijoon Lee, Jae Gwan Kim, "Simultaneous blood flow and oxygenation measurements using an off-the-shelf spectrometer," Chinese Optics Letters 16(7), 071701 (2018)

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