Chinese Optics Letters, 2011, 9 (2): 021701, Published Online: Mar. 3, 2011
Determination of myocardial ischemia and degree of reperfusion based on optical coherence tomography 
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光学相干断层成像 心肌缺血 再灌注 诊断 170.4580 Optical diagnostics for medicine 170.4500 Optical coherence tomography 170.2655 Functional monitoring and imaging
Abstract
The feasibility of applying optical coherence tomography (OCT) in determining the degree of myocardial ischemia-reperfusion injury is assessed. The left anterior descending coronary artery of 90 Sprague-Dawley rats are ligated and reperfused at different times. The total attenuation coefficient obtained from the OCT images in the experimental group keeps increasing with reperfusion time and highly correlates with the histopathological characteristics (P <0.01). We present evidence proving the feasibility of using OCT for evaluating myocardial ischemia reperfusion.
Haiyu Chen, Guoxing Weng, Zhifang Li, Hui Li, Xiamei Cai. Determination of myocardial ischemia and degree of reperfusion based on optical coherence tomography[J]. Chinese Optics Letters, 2011, 9(2): 021701.
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