针孔X射线荧光CT探测角度优化研究

郭静; 冯鹏; 邓露珍; 罗燕; 何鹏; 魏彪

doi:doi:10.3788/AOS202040.0111017

光学学报, 2020, 40 (1): 0111017, 网络出版: 2020-01-06

针孔X射线荧光CT探测角度优化研究下载： 1257次

Optimization of Detection Angle for Pinhole X-Ray Fluorescence Computed Tomography

郭静 ¹冯鹏 ^1,2,*邓露珍 ¹罗燕 ¹何鹏 ^1,2,**魏彪 ^1,2

作者单位

¹ 重庆大学光电技术及系统教育部重点实验室, 重庆 400044

² 重庆大学工业CT无损检测教育部工程研究中心, 重庆 400044

图 & 表

图 1. 针孔准直XFCT 原理示意图

Fig. 1. Diagram of XFCT with pinhole collimator

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图 2. 多针孔XFCT MC模型的示意图

Fig. 2. Schematic of multi-pinhole XFCT MC model

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图 3. 多孔准直及模体设计。(a)包含三个孔的铅板垂直视图;(b)一个孔的铅板的横截面示意图;(c)模体1;(d)模体2

Fig. 3. Designs of multi-pinhole collimator and phantom. (a) Perpendicular view of lead plate containing three pinholes; (b) cross-section of lead plate containing one pinhole; (c) phantom 1; (d) phantom 2

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图 4. X射线能谱及荧光光谱曲线。(a) X射线源能谱;(b)荧光光谱曲线

Fig. 4. Energy spectrum of X-ray source and spectrum of X-ray fluorescence. (a) Energy spectrum of X-ray source; (b) spectrum of X-ray fluorescence

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图 5. 不同管电压下的仿真结果。(a)不同管电压下噪声与探测角度的关系;(b)不同管电压、不同探测角度下的R_SN

Fig. 5. Simulation results at different tube voltages. (a) Noise as a function of detection angle at different tube voltages; (b) R_SN as a function of tube voltage at different detection angles

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图 6. 不同GNPs质量分数下的仿真结果。(a)不同GNPs质量分数下噪声与探测角度的关系;(b)不同GNPs质量分数、不同探测角度下的R_SN

Fig. 6. Simulation results at different mass fractions of GNPs. (a) Noise as a function of detection angle at different mass fractions of GNPs; (b) R_SN as a function of mass fraction of GNPs at different detection angles

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图 7. 不同ROI直径下的实验结果。(a)不同ROI直径下噪声与探测角度的关系;(b)不同ROI直径、不同探测角度下的R_SN

Fig. 7. Simulation results at different diameters of ROI. (a) Noise as a function of detection angle at different diameters of ROI; (b) R_SN as a function of diameter of ROI at different detection angles

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图 8. 不同探测角度下的R_SN。(a)不同ROI直径、不同探测角度下的R_SN;(b)不同GNPs溶液质量分数、不同探测角度下的R_SN

Fig. 8. R_SN at different detection angles. (a) R_SN as a function of diameter of ROI at different detection angles; (b) R_SN as a function of mass fraction of GNPs at different detection angles

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图 9. 重建图像。(a) 90°时模体2的重建图像;(b) 120°时模体2的重建图像

Fig. 9. Reconstructed images. (a) Reconstructed image of phantom 2 at detection angle of 90°; (b) reconstructed image of phantom 2 at detection angle of 120°

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图 10. 重建图像的ROI像素值均值与R_CN。(a)重建图像的ROI像素值均值;(b) 90°和120°的R_CN

Fig. 10. Mean value and R_CN of ROI pixel values in reconstructed images. (a) Mean value of ROI pixel values in reconstructed images; (b) R_CN at detection angles of 90° and 120°

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表 1不同模拟组模体1参数

Table1. Parameters for phantom 1 in different simulation groups

Experiment	Phantom 1
Experiment	Tube voltage V_src /kV	GNPs mass fraction ρ /%	ROI diameter D_ROI /mm
1	90,100,110,120	2	6
2	120	0.25,0.50,1,2	6
3	120	1	4,6,8,10

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表 2模体2参数

Table2. Parameters for phantom 2

Experiment	Phantom 2
	Tube voltage V_src /kV	GNPs mass fraction ρ /%				ROI diameter D_ROI /mm
	Tube voltage V_src /kV		ROI₁	ROI₂	ROI₃	ROI₄
4	120	0.25	0.50	0.75	1	3

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郭静, 冯鹏, 邓露珍, 罗燕, 何鹏, 魏彪. 针孔X射线荧光CT探测角度优化研究[J]. 光学学报, 2020, 40(1): 0111017. Jing Guo, Peng Feng, Luzhen Deng, Yan Luo, Peng He, Biao Wei. Optimization of Detection Angle for Pinhole X-Ray Fluorescence Computed Tomography[J]. Acta Optica Sinica, 2020, 40(1): 0111017.

针孔X射线荧光CT探测角度优化研究下载： 1257次

图 1. 针孔准直XFCT 原理示意图

Fig. 1. Diagram of XFCT with pinhole collimator

图 2. 多针孔XFCT MC模型的示意图

Fig. 2. Schematic of multi-pinhole XFCT MC model

图 3. 多孔准直及模体设计。(a)包含三个孔的铅板垂直视图;(b)一个孔的铅板的横截面示意图;(c)模体1;(d)模体2

Fig. 3. Designs of multi-pinhole collimator and phantom. (a) Perpendicular view of lead plate containing three pinholes; (b) cross-section of lead plate containing one pinhole; (c) phantom 1; (d) phantom 2

图 4. X射线能谱及荧光光谱曲线。(a) X射线源能谱;(b)荧光光谱曲线

Fig. 4. Energy spectrum of X-ray source and spectrum of X-ray fluorescence. (a) Energy spectrum of X-ray source; (b) spectrum of X-ray fluorescence

图 5. 不同管电压下的仿真结果。(a)不同管电压下噪声与探测角度的关系;(b)不同管电压、不同探测角度下的R_SN

Fig. 5. Simulation results at different tube voltages. (a) Noise as a function of detection angle at different tube voltages; (b) R_SN as a function of tube voltage at different detection angles

图 6. 不同GNPs质量分数下的仿真结果。(a)不同GNPs质量分数下噪声与探测角度的关系;(b)不同GNPs质量分数、不同探测角度下的R_SN

Fig. 6. Simulation results at different mass fractions of GNPs. (a) Noise as a function of detection angle at different mass fractions of GNPs; (b) R_SN as a function of mass fraction of GNPs at different detection angles

图 7. 不同ROI直径下的实验结果。(a)不同ROI直径下噪声与探测角度的关系;(b)不同ROI直径、不同探测角度下的R_SN

Fig. 7. Simulation results at different diameters of ROI. (a) Noise as a function of detection angle at different diameters of ROI; (b) R_SN as a function of diameter of ROI at different detection angles

图 8. 不同探测角度下的R_SN。(a)不同ROI直径、不同探测角度下的R_SN;(b)不同GNPs溶液质量分数、不同探测角度下的R_SN

Fig. 8. R_SN at different detection angles. (a) R_SN as a function of diameter of ROI at different detection angles; (b) R_SN as a function of mass fraction of GNPs at different detection angles

图 9. 重建图像。(a) 90°时模体2的重建图像;(b) 120°时模体2的重建图像

Fig. 9. Reconstructed images. (a) Reconstructed image of phantom 2 at detection angle of 90°; (b) reconstructed image of phantom 2 at detection angle of 120°

图 10. 重建图像的ROI像素值均值与R_CN。(a)重建图像的ROI像素值均值;(b) 90°和120°的R_CN

Fig. 10. Mean value and R_CN of ROI pixel values in reconstructed images. (a) Mean value of ROI pixel values in reconstructed images; (b) R_CN at detection angles of 90° and 120°

表 1不同模拟组模体1参数

Table1. Parameters for phantom 1 in different simulation groups

表 2模体2参数

Table2. Parameters for phantom 2

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图 1. 针孔准直XFCT 原理示意图

Fig. 1. Diagram of XFCT with pinhole collimator

图 2. 多针孔XFCT MC模型的示意图

Fig. 2. Schematic of multi-pinhole XFCT MC model

图 3. 多孔准直及模体设计。(a)包含三个孔的铅板垂直视图;(b)一个孔的铅板的横截面示意图;(c)模体1;(d)模体2

Fig. 3. Designs of multi-pinhole collimator and phantom. (a) Perpendicular view of lead plate containing three pinholes; (b) cross-section of lead plate containing one pinhole; (c) phantom 1; (d) phantom 2

图 4. X射线能谱及荧光光谱曲线。(a) X射线源能谱;(b)荧光光谱曲线

Fig. 4. Energy spectrum of X-ray source and spectrum of X-ray fluorescence. (a) Energy spectrum of X-ray source; (b) spectrum of X-ray fluorescence

图 5. 不同管电压下的仿真结果。(a)不同管电压下噪声与探测角度的关系;(b)不同管电压、不同探测角度下的RSN

Fig. 5. Simulation results at different tube voltages. (a) Noise as a function of detection angle at different tube voltages; (b) RSN as a function of tube voltage at different detection angles

图 6. 不同GNPs质量分数下的仿真结果。(a)不同GNPs质量分数下噪声与探测角度的关系;(b)不同GNPs质量分数、不同探测角度下的RSN

Fig. 6. Simulation results at different mass fractions of GNPs. (a) Noise as a function of detection angle at different mass fractions of GNPs; (b) RSN as a function of mass fraction of GNPs at different detection angles

图 7. 不同ROI直径下的实验结果。(a)不同ROI直径下噪声与探测角度的关系;(b)不同ROI直径、不同探测角度下的RSN

Fig. 7. Simulation results at different diameters of ROI. (a) Noise as a function of detection angle at different diameters of ROI; (b) RSN as a function of diameter of ROI at different detection angles

图 8. 不同探测角度下的RSN。(a)不同ROI直径、不同探测角度下的RSN;(b)不同GNPs溶液质量分数、不同探测角度下的RSN

Fig. 8. RSN at different detection angles. (a) RSN as a function of diameter of ROI at different detection angles; (b) RSN as a function of mass fraction of GNPs at different detection angles

图 9. 重建图像。(a) 90°时模体2的重建图像;(b) 120°时模体2的重建图像

Fig. 9. Reconstructed images. (a) Reconstructed image of phantom 2 at detection angle of 90°; (b) reconstructed image of phantom 2 at detection angle of 120°

图 10. 重建图像的ROI像素值均值与RCN。(a)重建图像的ROI像素值均值;(b) 90°和120°的RCN

Fig. 10. Mean value and RCN of ROI pixel values in reconstructed images. (a) Mean value of ROI pixel values in reconstructed images; (b) RCN at detection angles of 90° and 120°

表 1不同模拟组模体1参数

Table1. Parameters for phantom 1 in different simulation groups

表 2模体2参数

Table2. Parameters for phantom 2

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针孔X射线荧光CT探测角度优化研究下载： 1257次

图 5. 不同管电压下的仿真结果。(a)不同管电压下噪声与探测角度的关系;(b)不同管电压、不同探测角度下的R_SN

Fig. 5. Simulation results at different tube voltages. (a) Noise as a function of detection angle at different tube voltages; (b) R_SN as a function of tube voltage at different detection angles

图 6. 不同GNPs质量分数下的仿真结果。(a)不同GNPs质量分数下噪声与探测角度的关系;(b)不同GNPs质量分数、不同探测角度下的R_SN

Fig. 6. Simulation results at different mass fractions of GNPs. (a) Noise as a function of detection angle at different mass fractions of GNPs; (b) R_SN as a function of mass fraction of GNPs at different detection angles

图 7. 不同ROI直径下的实验结果。(a)不同ROI直径下噪声与探测角度的关系;(b)不同ROI直径、不同探测角度下的R_SN

Fig. 7. Simulation results at different diameters of ROI. (a) Noise as a function of detection angle at different diameters of ROI; (b) R_SN as a function of diameter of ROI at different detection angles

图 8. 不同探测角度下的R_SN。(a)不同ROI直径、不同探测角度下的R_SN;(b)不同GNPs溶液质量分数、不同探测角度下的R_SN

Fig. 8. R_SN at different detection angles. (a) R_SN as a function of diameter of ROI at different detection angles; (b) R_SN as a function of mass fraction of GNPs at different detection angles

图 10. 重建图像的ROI像素值均值与R_CN。(a)重建图像的ROI像素值均值;(b) 90°和120°的R_CN

Fig. 10. Mean value and R_CN of ROI pixel values in reconstructed images. (a) Mean value of ROI pixel values in reconstructed images; (b) R_CN at detection angles of 90° and 120°