激光与光电子学进展, 2020, 57 (12): 120004, 网络出版: 2020-06-03   

基于环形阵列式传感器的光声层析成像研究进展 下载: 1663次

Recent Advances in Photoacoustic Tomography Based on Circular Array Transducer
作者单位
1 江西科技师范大学光电子与通信重点实验室, 江西 南昌 330038
2 广东工业大学精密电子制造技术与装备国家重点实验室, 广东 广州 510006
图 & 表

图 1. Oeri小组设计的实验系统和手指层析成像结果。(a)系统框图;(b1)外围趾关节和远端指间关节最大强度投影;(b2)左小指轴向切片;(b3)健康志愿者左小指[39]

Fig. 1. Experimental system designed by the Oeri group. (a) System block diagram; (b1) maximum intensity projection of peripheral toe joint and distal interphalangeal joint; (b2) axial slice display of left little finger; (b3) left little finger of healthy volunteer[39]

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图 2. 本课题组设计的实验系统及成像结果。(a)系统框图;(b)猪眼内铜丝异物的光声成像图,插图为插入铜丝的照片;(c)兔脑皮层血管的光声成像图,插图为实验后兔脑的开颅图像[44-47]

Fig. 2. Experimental system designed by our group and imaging results. (a) System block diagram; (b) photoacoustic image of the intraocular copper-wire and the inserted is the photograph of the copper wire; (c) photoacoustic imaging of brain cortical vasculature of the rabbit, where the inset is the open-skull photograph of the rabbit brain after experiments [44-47]

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图 3. 志愿者右手的光声成像。(a)沿Z轴光声信号最大幅值投影;(b)手部深度图像的彩色编码[50]

Fig. 3. Photoacoustic images of the volunteer's right hand. (a) Maximum amplitude projection of the photoacoustic signals along the Z-axis; (b) color encoded depth image of the hand [50]

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图 4. Nagae小组设计的实验系统和四肢光声成像结果。(a)实验装置及数据采集框图;(b)手掌;(c)手背;(d)前臂;(e)大腿外侧;(f)小腿;(g)脚尖;(h)脚底;(i) b~h对应的位置[51]

Fig. 4. Experimental system designed by the Nagae group and photoacoustic imaging of the limbs. (a) Experimental device and data acquisition block diagram; (b) palm; (c) back of hand; (d) forearm; (e) outside of thigh; (f) calf; (g) toe; (h) foot sole; (i) b-h corresponding position [51]

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图 5. Heijblom小组设计的实验系统和实验结果。(a)系统框图;(b)~(e)为胸腺在头尾位方向下的两个病例的MRI(左侧)和PAT(右侧)数据重建[63]

Fig. 5. Experimental system designed by Heijblom group and experimental results. (a) System block diagram; (b)-(e) MRI (left) and PAT (right) data reconstruction of two cases of thymus in the head and tail position[63]

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图 6. Tang小组设计的实验系统和大脑中血氧浓度变化。(a)可穿戴式超声传感器结构图;(b)设计的系统框图;(c)可穿戴式超声传感器下的行为能力;(d)脑血红蛋白成像;(e)平面内氧饱和度[65]

Fig. 6. Experimental system designed by Tang group and the changes of the blood oxygen concentration in the brain. (a) Structure of wearable ultrasonic transducer; (b) design of the system diagram; (c) behavioral capabilities under a wearable ultrasonic transducer; (d) total cerebral hemoglobin images; (e) oxygen saturation in plane[65]

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表 1基于线性传感器阵列的光声层析成像系统性能

Table1. Performance of photoacoustic tomography system based on linear transducer arrays

GroupUSNumbers ofarrayLateralresolution /μmImagingdepth /mmImagingspeed /(frame·s-1)LaserilluminationApplication
Meng[12]CF: 30 MHzB: 70%488080.143W: 584 nmE: 0.5 mJ/cm2humanhands、 rat
Zemp[13]CF: 30 MHzB: 70%4840950W: 578 nm/571 nmE: 5-10 mJ/cm2nude mice
Yang[14]CF: 7.5 MHz128180300.156W: 532 nmE: 200 mJ/cm2rat
Li[15]CF: 40 MHzB: 82.5%2566020-W: 532 nmE: 11 mJ/cm2zebrafish
W-wavelength; E-energy; CF-central frequency; B-bandwidth; US-ultrasonic transducer array

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表 2环形超声传感器阵列的类型和性能

Table2. Types and performance of circular ultrasonic transducer arrays

GroupUSStyleNumberSize /mmMaterial
Oeri[39]CF: 14 MHzB:107.1%arc2560.138×3CMUT
Yang[44]CF: 7.5 MHzB: 75%full-arc2568×1.06PZT
Nagae[51]CF: 3.34 MHzB:85 %hemispherical1024diameter: 21-3 PZT/ epoxy resin
Heijblom[63]CF: 1 MHzB: 130%circularplane5882×2PVDF
Tang[64]CF: 8.1 MHzB: 75.4%wearable641.47×5PVDF

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张国鹏, 邓丽军, 白杨, 刘国栋, 曾吕明, 纪轩荣. 基于环形阵列式传感器的光声层析成像研究进展[J]. 激光与光电子学进展, 2020, 57(12): 120004. Guopeng Zhang, Lijun Deng, Yang Bai, Guodong Liu, Lüming Zeng, Xuanrong Ji. Recent Advances in Photoacoustic Tomography Based on Circular Array Transducer[J]. Laser & Optoelectronics Progress, 2020, 57(12): 120004.

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