谱域OCT成像系统在口腔组织检测中的应用

基于谱域光学相干层析术理论设计并搭建了一套便于集成化的光纤式谱域OCT系统, 其纵向分辨率为7.3 μm, 横向分辨率为9.5 μm, 在空气中的成像深度为3.14 mm。该系统通过干涉光谱来获得样品的深度信息, 实现数据的高速采集。利用该系统对口腔内唾液腺导管内壁的组织形态进行了研究, 并将得到的OCT图像与相对应的病理切片图片进行了比较。实验结果表明, 采用研制的系统可以获得腮腺导管内壁组织的层析结构。该项研究对临床医学上的口腔唾液腺疾病的无创检查和早期诊断具有指导意义。

Abstract

On the basis of the concept of Spectral Domain Optical Coherence Tomography (SDOCT),a fiber type SDOCT system which is easy to integration was developed. The system shows its longitudinal resolution in 7.3 μm, lateral resolution in 9.5 μm and offers the imaging depth to be 3.14 mm in air. The system obtains the sample deeply by a interferometer, which achieves the dada collection fast. The organizational features of salivary glands were researched by the above system, and the OCT images for the parotid glands were compared with that of the pathological section. Results show that the system proposed can provide a direction for the early diagnosis and the non-harmful examination of the oral cavity tissue.

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彭诚, 张芹芹, 吴晓静, 朱思伟, 高志, 袁小聪. 谱域OCT成像系统在口腔组织检测中的应用[J]. 光学精密工程, 2011, 19(8): 1931. PENG Cheng, ZHANG Qin-qin, WU Xiao-jing, ZHU Si-wei, GAO Zhi, YUAN Xiao-cong. Application of spectral domain optical coherence tomography to oral cavity tissue test[J]. Optics and Precision Engineering, 2011, 19(8): 1931.

谱域OCT成像系统在口腔组织检测中的应用

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