Journal of Innovative Optical Health Sciences, 2017, 10 (3): 1750002, Published Online: Dec. 27, 2018  

Rapid monitoring the water extraction process of Radix Paeoniae Alba using near infrared spectroscopy

Author Affiliations
1 School of Pharmaceutical Sciences, Shandong University, Wenhuaxi Road 44, Jinan, 250012, P. R. China
2 Shandong Wohua Pharmaceutical Technology Co., Ltd, Weifang, 261205, P. R. China
Abstract
Near infrared (NIR) spectroscopy has been developed into one of the most important process analytical techniques (PAT) in a wide field of applications. The feasibility of NIR spectroscopy with partial least square regression (PLSR) to monitor the concentration of paeoniflorin, albiflorin, gallic acid, and benzoyl paeoniflorin during the water extraction process of Radix Paeoniae Alba was demonstrated and verified in this work. NIR spectra were collected in transmission mode and pretreated with smoothing and/or derivative, and then quantitative models were built up using PLSR. Interval partial least squares (iPLS) method was used for the selection of spectral variables. Determination coe±cients (R2 cal and R2 pred), root mean squares error of prediction (RMSEP), root mean squares error of calibration (RMSEC), and residual predictive deviation (RPD) were applied to verify the performance of the models, and the corresponding values were 0.9873 and 0.9855, 0.0487 mg/mL, 0.0545 mg/mL and 8.4 for paeoniflorin; 0.9879, 0.9888, 0.0303 mg/mL, 0.0321 mg/mL and 9.1 for albiflorin; 0.9696, 0.9644, 0.0140 mg/mL, 0.0145 mg/mL and 5.1 for gallic acid; 0.9794, 0.9781, 0.00169 mg/mL, 0.00171 mg/mL and 6.9 for benzoyl paeoniflorin, respectively. The results turned out that this approach was very e±cient and environmentally friendly for the quantitative monitoring of the water extraction process of Radix Paeoniae Alba.
References

[1] W. Li, S. Huang, R. Wang, “Advances in research on pharmacological actions and quality control of Paeoniae Radix Alba, ” Pharm. Care Res. 2, 016 (2012).

[2] C. H. Wang, R. Wang, X. M. Cheng, Y. Q. He, Z. T. Wang, C. Wu, J. Cao, “Comparative pharmacokinetic study of paeoniflorin after oral administration of decoction of Radix Paeoniae Rubra and Radix Paeoniae Alba in rats, ” J. Ethnopharmacol. 117, 467–472 (2008).

[3] H. Ohta, J. W. Ni, K. Matsumoto, H. Watanabe, M. Shimizu, “Peony and its major constituent, paeoniflorin, improved radial maze performance impaired by scopolamine in rats, ” Pharmacol. Biochem. Behav. 45, 719–723 (1993).

[4] State Pharmacopoeia Committee of People’s Republic of China, Chinese Pharmacopoeia, Chemical Industry Press, Beijing (2015).

[5] K. S. Suh, E. M. Choi, Y. S. Lee, Y. S. Kim, “Protective effect of albiflorin against oxidative-stress-mediated toxicity in osteoblast-like MC3T3-E1 cells, ” Fitoterapia 89, 33–41 (2013).

[6] T. Okubo, F. Nagai, T. Seto, K. Satoh, K. Ushiyama, I. Kano, “The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix, ” Biol. Pharm. Bull. 23, 199–203 (2000).

[7] G. C. Yen, P. D. Duh, H. L. Tsai, “Antioxidant and pro-oxidant properties of ascorbic acid and gallic acid, ” Food Chemistry 79, 307–313 (2002).

[8] J. P. Fan, J. Cao, X. H. Zhang, J. Z. Huang, T. Kong, S. Tong, Z. Y. Tian, Y. L. Xie, R. Xu, J. H. Zhu, “Optimization of ionic liquid based ultrasonic assisted extraction of puerarin from Radix Puerariae Lobatae by response surface methodology, ” Food Chemistry 135, 2299–306 (2012).

[9] Q. Dong, H. Zang, A. Liu, G. Yang, C. Sun, L. Sui, P. Wang, L. Li, “Determination of molecular weight of hyaluronic acid by near-infrared spectroscopy, ” J. Pharm. Biomed. Anal. 53, 274–278 (2010).

[10] H. Huang, H. Yu, H. Xu, Y. Ying, “Near infrared spectroscopy for on/in-line monitoring of quality in foods and beverages: A review, ” J. Food Eng. 87, 303–313 (2008).

[11] P. Wang, Z. Yu, “Species authentication and geographical origin discrimination of herbal medicines by near infrared spectroscopy: A review, ” J. Pharm. Anal. 5, 277–284 (2015). Crossref,

[12] E. W. Ciurczak, B. Igne, Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy, CRC Press (2014).

[13] A. Rohman, A. Nugroho, E. Lukitaningsih, Sudjadi, “, Application of Vibrational Spectroscopy in Combination with Chemometrics Techniques for Authentication of Herbal Medicine, ” Appl. Spectrosc. Rev. 49, 603–613 (2014).

[14] F. Wang, W. Jiang, C. Li, H. Zhang, L. Nie, L. Li, P. Wang, H. Zang, “Application of near infrared spectroscopy in monitoring the moisture content in freeze-drying process of human coagulation factor VIII, ” J. Innov. Opt. Health Sci. 8, 1550034 (2015). Link, ISI,

[15] P. Wang, J. Sun, T. Zhang, W. Liu, “Vibrational spectroscopic approaches for the quality evaluation and authentication of virgin olive oil, ” Appl. Spectrosc. Rev. 51, 763–790 (2016).

[16] X. L. Chu, Y. P. Xu, W. Z. Lu, “Research and Application Progress of Chemometrics Methods in Near Infrared Spectroscopic Analysis, ” Chinese J. Anal. Chem. 5, 031 (2008).

[17] H. Liu, X. Zhao, T. Qi, Y. P. Qi, G. R. Fan, “Establishment of the model for online monitoring of the column separation and purification process by near-infrared spectroscopy and determination of total ginsenosides in Folium Ginseng, ” Guang pu xue yu guang pu fen xi = Guang pu 33, 3226–3230 (2013).

[18] Y. Wu, Y. Jin, H. Ding, L. Luan, Y. Chen, X. Liu, “In-line monitoring of extraction process of scutellarein from Erigeron breviscapus (vant.) Hand-Mazz based on qualitative and quantitative uses of near-infrared spectroscopy, ” Spectrochim. Acta A, Mol. Biomol. Spectrosc. 79, 934–939 (2011).

[19] Z. Wu, C. Sui, B. Xu, L. Ai, Q. Ma, X. Shi, Y. Qiao, “Multivariate detection limits of on-line NIR model for extraction process of chlorogenic acid from Lonicera japonica, ” J. Pharm. Biomed. Anal. 77, 16–20 (2013).

[20] P. Wang, H. Zhang, H. Yang, L. Nie, H. Zang, “Rapid determination of major bioactive isoflavonoid compounds during the extraction process of kudzu (Pueraria lobata) by near-infrared transmission spectroscopy, ” Spectrochim. Acta A, Mol. Biomol. Spectrosc. 137, 1403–1408 (2015).

[21] Z. Wu, B. Xu, M. Du, C. Sui, X. Shi, Y. Qiao, “Validation of a NIR quantification method for the determination of chlorogenic acid in Lonicera japonica solution in ethanol precipitation process, ” J. Pharm. Biomed. Anal. 62, 1–6 (2012).

[22] P. C. Williams, D. C. Sobering, How do we do it: A brief summary of the methods we use in developing near infrared calibrations, Near Infrared Spectroscopy: The Future Waves, 185–188 (1996).

Tian Hu, Tongtong Li, Lei Nie, Lixuan Zang, Hengchang Zang, Yingzi Zeng. Rapid monitoring the water extraction process of Radix Paeoniae Alba using near infrared spectroscopy[J]. Journal of Innovative Optical Health Sciences, 2017, 10(3): 1750002.

关于本站 Cookie 的使用提示

中国光学期刊网使用基于 cookie 的技术来更好地为您提供各项服务,点击此处了解我们的隐私策略。 如您需继续使用本网站,请您授权我们使用本地 cookie 来保存部分信息。
全站搜索
您最值得信赖的光电行业旗舰网络服务平台!