光学 精密工程, 2007, 15 (7): 1056, 网络出版: 2008-02-18  

简易低成本柔性神经微电极制作方法

A simple and low-cost method to fabricate flexible microelectrodes for neural applications
作者单位
1 中国科学院上海微系统与信息技术研究所,上海,200050
2 中国科学院研究生院,北京,100039
3 上海交通大学激光与生物医学研究所,上海,200030
摘要
提出了一种简单、低成本的植入式柔性薄膜神经微电极的制作工艺和方法.该方法采用光敏型聚酰亚胺(Durimide 7510)代替传统方法中的非光敏型聚酰亚胺或聚对二甲苯作为微电极基质材料,同时设计了一种基于应力集中的凹槽结构以保证所得微电极形状的规整性,且采用了一种基于硅导电性通过电化学腐蚀牺牲层的方法来实现微电极从支撑基片表面的完整自动释放.整个制作工艺简单,仅需两次光刻和两次金属沉积.测试和评价了所制作微电极的表面形貌、电学性能以及生物相容性,结果表明,这种方法大大降低了制作成本并缩短了周期.
Abstract
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周洪波, 李刚, 张华, 孙晓娜, 姚源, 金庆辉, 赵建龙, 任秋实. 简易低成本柔性神经微电极制作方法[J]. 光学 精密工程, 2007, 15(7): 1056. 周洪波, 李刚, 张华, 孙晓娜, 姚源, 金庆辉, 赵建龙, 任秋实. A simple and low-cost method to fabricate flexible microelectrodes for neural applications[J]. Optics and Precision Engineering, 2007, 15(7): 1056.

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