Q开关532 nm与755 nm激光治疗咖啡斑的疗效对比

沈菊芳; 富秋涛; 孟辉

doi:doi:10.3969/j.issn.1007-7146.2018.05.011

激光生物学报, 2018, 27 (6): 551, 网络出版: 2019-02-14

Q开关532 nm与755 nm激光治疗咖啡斑的疗效对比

Assessment of Therapeutic Efficacy of Q-switched 532 nm and 755 nm Laser in Treatment of Cafe-au-lait

论文大纲

沈菊芳富秋涛 ^*孟辉

作者单位

解放军空军总医院, 北京100142

咖啡斑 Q开关532 nm激光 Q开关755 nm激光临床效果 cafe-au-lait Q-switched 532 nm laser Q-switched 755 nm laser clinical efficacy

摘要

本中心回顾性研究咖啡斑患者84例, 随机给予Q开关532 nm和755 nm激光治疗, 观察临床效果。结果显示, Q开关532 nm激光治疗36例, 痊愈10例(27.8%), 显效10例(27.8%), 有效8例(22.2%), 无效8例(22.2%)；Q开关755 nm激光治疗48例, 痊愈14例(29.2%), 显效13例(27.1%), 有效11例(22.9%), 无效10例(20.8%), 84例患者总有效率78.6%。术后半年随访, 色素沉着9例, 色素减退3例, 复发9例。Q开关激光治疗形状不规则的咖啡斑有效率为79.5%, 治疗形状规则的咖啡斑有效率为52.5%, 两组治疗的有效率差异有统计学意义(P＜0.05), Q开关532 nm激光和Q开关755 nm激光对咖啡斑的治疗效果无显著的统计学差异(P＞0.05)。以上结果表明, Q开关532 nm激光和Q开关755 nm激光对咖啡斑有明确的治疗效果, 且外形不规则的咖啡斑治疗效果好。

Abstract

Eighty four patients with cafe-au-lait were treated with Q-switched 532 nm or 755 nm laser randomly by our center. The clinical efficacy was assessed. 36 patients were treated with Q-switched 532 nm laser, 10 patients were completely cured (27.8%), 10 patients were significantly improved (27.8%), 8 improved (22.2%) and 8 invalid (22.2%); 48 patients were treated with Q-switched 755 nm laser, 14 patients were cured completely (29.2%), 13 patients were significantly improved (27.1%), 11 improved (22.9%) and 10 invalid (20.8%). Of the 84 patients, total effective rate is 78.6%. After 6 months of follow-up, 9 patients appeared pigmentation, 3 patients appeared hypopigmentation and 9 recrudesced. The effective rate of cafe-au-lait with regular shape is 52.5%, and irregular shape is 79.5%, there was a significant difference between two teams (P＜0.05). There was no significant difference in efficacy between Q-switched 532 nm and 755 nm laser (P＞0.05). The above results showed Q-switched 532 nm and 755 nm laser were effective agents for treatment of cafe-au-lait., and the efficacy of Q-switched laser on cafe-au-lait with regular shape is better than those with irregular shape．

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沈菊芳, 富秋涛, 孟辉. Q开关532 nm与755 nm激光治疗咖啡斑的疗效对比[J]. 激光生物学报, 2018, 27(6): 551. SHEN Jufang, FU Qiutao, MENG Hui. Assessment of Therapeutic Efficacy of Q-switched 532 nm and 755 nm Laser in Treatment of Cafe-au-lait[J]. Acta Laser Biology Sinica, 2018, 27(6): 551.

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