Journal of Innovative Optical Health Sciences, 2016, 9 (4): 1630006, Published Online: Dec. 27, 2018  

Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy

Author Affiliations
Ministry of Education Key Laboratory of Laser Life Science & Institute of Laser Life Science College of Biophotonics South China Normal University Guangzhou 510631, P. R. China
Abstract
Upconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates for bioimaging and therapy application. This review aims at summarizing the synthesis and modification of UCNPs, especially the applications of UCNPs as a theranostic agent for tumor imaging and therapy. The biocompatibility and toxicity of UCNPs are also further discussed. Finally, we discuss the challenges and opportunities in the development of UCNP-based nanoplatforms for tumor imaging and therapy.
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Wenkai Fang, Yanchun Wei. Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy[J]. Journal of Innovative Optical Health Sciences, 2016, 9(4): 1630006.

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