Author Affiliations
Abstract
1 MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics South China Normal University Guangzhou 510631, P. R. China
2 Department of Ophthalmology Xinhua Hospital, Shanghai Jiaotong University School of Medicine Shanghai 200092, P. R. China
3 Shenzhen Key Laboratory for Minimal Invasive Medical Technologies Graduate School at Shenzhen, Tsinghua University Shenzhen 518055, P. R. China
4 MOE Key Laboratory of Laser Life Science College of Biophotonics, South China Normal University Guangzhou 510631, P. R. China
We proposed a new saccharides sensor developed by symmetrical optical waveguide (SOW)- based surface plasmon resonance (SPR). This unique MgF2/Au/MgF2/Analyte film structure results in longer surface plasmon wave (SPW) propagation lengths and depths, leading to an increment of resolution. In this paper, we managed to decorate the dielectric interface (MgF2 layer) by depositing a thin polydopamine film as surface-adherent that provides a platform for secondary reactions with the probe molecule. 3-Aminophenylboronic acid (3-PBA) is chosen to be the saccharides sense probe molecule in the present work. The aqueous humor of Diabetes and Cataract patient whose blood glucose level is normal are analyzed and the results demonstrated that this sensor shows great potential in monitoring the blood sugar and can be adapted in the field of biological monitoring in the future.
Saccharides sensor surface plasmon resonance symmetrical optical waveguide 3-Aminophenylboronic acid dopamine Journal of Innovative Optical Health Sciences
2015, 8(2): 1550003