We proposed a new saccharides sensor developed by symmetrical optical waveguide (SOW)- based surface plasmon resonance (SPR). This unique MgF₂/Au/MgF₂/Analyte film structure results in longer surface plasmon wave (SPW) propagation lengths and depths, leading to an increment of resolution. In this paper, we managed to decorate the dielectric interface (MgF₂ layer) by depositing a thin polydopamine film as surface-adherent that provides a platform for secondary reactions with the probe molecule. 3-Aminophenylboronic acid (3-PBA) is chosen to be the saccharides sense probe molecule in the present work. The aqueous humor of Diabetes and Cataract patient whose blood glucose level is normal are analyzed and the results demonstrated that this sensor shows great potential in monitoring the blood sugar and can be adapted in the field of biological monitoring in the future.

表面等离子体共振(SPR)传感系统有角度谱、光谱、强度、相位等解调方式, 其中光谱型的(SPR)传感系统因可以使用光纤导光, 将传感部分独立出来, 可进行远距离传感和现场检测, 并能有效缩小系统的体积。对称光波导型(SOW)SPR因金属膜层两边的折射率完全相同, 表面等离子体波传播距离更长, 穿透深度更深, 比传统的SPR系统具有更高的灵敏度和分辨率。对对称波导型(SOW)SPR进行光谱解调研究, 以MgF2-Au-MgF2结构的SOW-SPR为传感单元, 同时以光纤输出的卤素灯为光源, 搭建了一套光谱解调的SOW-SPR检测系统, 以不同浓度的葡萄糖溶液对系统折射率分辨率进行测量, 得到2.8×10－7 RIU的分辨率。为SOW-SPR系统小型化、现场检测以及远距离探测提出一种可能实现的手段, 具有很好的应用前景。