中国激光医学杂志, 2006, 15 (1): 56, 网络出版: 2006-08-09   

生物系统光响应的剂量关系

Photonic Response of a Biological System in Correlation with Light Doses
作者单位
1 华南师范大学激光运动医学实验室,广州市,510631
2 华南师范大学生命科学学院
3 华南师范大学信息光电子科技学院
摘要
激光或单色光对生物系统(biological system,BS)的作用将改变BS的性质或功能,这个过程称之为BS光响应(pho-tonic response of a BS,PBS).细胞的光响应包括细胞增殖、分化、黏附、凋亡和光动力效应(photodynamic effect,PDE)等.伤口的光响应包括伤口愈合等.PBS的剂量关系是光疗研究的一个十分重要但常常被忽视的问题,一篇结果很好的论文往往可能因为剂量没有陈述清楚而大大降低其参考价值[1,2].国际上光生物调节作用(photobiomodulation,PBM)[3-6]的研究中,有些研究小组可能是由于忽视剂量关系的研究,所以发表了实验结果否定PBM的论文,这可能是造成PBM研究极大混乱的一个原因.国内PBM用于血管内、鼻腔内和穴位照射的临床应用中也忽视了剂量关系的研究,可能正是由于这样,才造成疗效严重下降,激光针灸已经基本上从临床上消失,血管内照射和鼻腔内照射的临床应用受到卫生部的严格限制[6].本文主要讨论PDE和PBM中PBS的剂量关系,再一次呼吁同行们高度重视PBS剂量关系的研究.……
Abstract
参考文献

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吴敏, 刘承宜, 程蕾, 王双喜, 郭红, 刘颂豪. 生物系统光响应的剂量关系[J]. 中国激光医学杂志, 2006, 15(1): 56. 吴敏, 刘承宜, 程蕾, 王双喜, 郭红, 刘颂豪. Photonic Response of a Biological System in Correlation with Light Doses[J]. Chinese Journal of Laser Medicine & Surgery, 2006, 15(1): 56.

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