束流轨道优化是短波长自由电子激光调试放大过程的关键环节。在实际实验中，需要花费大量的时间来调整参数，以校正轨道。为简化该多参数调优过程，研究了基于深度强化学习的自动优化技术，在仿真环境中使用SAC、TD3和DDPG算法调整多个校正磁铁，以优化自由电子激光的输出功率。为模拟实际实验中非理想的轨道状态，在第一节波荡器入口处设置一磁铁以偏转束流轨道。随后利用深度强化学习算法自动调节后续7个磁铁以校正轨道。结果表明，通过引入偏差将输出功率降低一个数量级后，基于最大熵原理的SAC算法将功率恢复到初始值的98.7%，优于TD3与DDPG算法。此外，SAC算法表现出更强的鲁棒性，有望后续应用在我国X射线自由电子激光装置中实现自动调束。

针对目前水质参数传感器测量功能单一, 且受环境温度影响大等问题, 提出了一种具有温度补偿功能的多参数水质传感器芯片。该传感器芯片是使用微机电系统(MEMS)技术制造的, 芯片表面集成了pH传感器、DO传感器、氨氮传感器和温度传感器。为实现温度补偿, 芯片还设计了一种夹心板式蛇形Pt电阻加热器。同时设计了与芯片相适应的微流控测试腔, 以实现水样测量。采用有限元稳态热分析对4种加热器热传递过程进行分析, 得到合理的芯片结构布局, 通过MEMS工艺制作出传感器芯片。采用自制的恒电位仪测试电路, 对传感器芯片性能进行了测试。实验结果表明, pH传感器具有0.288 mA/pH的高灵敏度; 溶解氧(DO)传感器的灵敏度为2.22 μA/(mg·L-1); 氨氮传感器的灵敏度为0.113 9 mA/(mg·L-1); 温度传感器的灵敏度为0.949 Ω/℃; 加热器的功率和温度变化灵敏度为0.312 6 ℃/mW。与单个水质参数传感器相比, 该传感器芯片体积小、坚固耐用, 能够同时检测水样的多种参数, 且温度补偿效果较好。

Metasurface provides subwavelength structures for manipulating wavefronts of light. The benefits of subwavelength components offer a continuous modulation of amplitude, phase, and polarization, thus eliminating the production of higher-order images and improving the utilization of light intensity. Despite the rapid progress in this field, multiparameter control of light using single layer metasurface is rarely reported. In fact, multiparameter control of light helps to improve information storage capacity and image fidelity. With simultaneous manipulation of polarization and amplitude at each pixel, it is possible to encode two separate images into one metasurface and reconstruct them under proper conditions. In a proof of concept experiment, we demonstrate an independent display of two binary images at the same position with polarization de-multiplexing from a single metasurface. This unique technology of encoding two images through amplitude and polarization manipulation provides a new opportunity for various applications in, such as encryption, information storage, polarization holograms, optical communications and fundamental physics.

光声显微成像技术是近年发展迅速的一种基于光学吸收差异的成像技术，它继承了光学成像对比度高、超声成像深度深的优点，表现出纯光学显微成像技术所无法比拟的优越性。光声显微成像实现了从声学分辨率至光学分辨率的多尺度成像，发展出从单纯的吸收结构到功能的多参量成像、从依靠内源吸收体到外源对比剂的多对比度成像、从依赖超声换能器到全光学激发与探测、从单一吸收成像到与光学相干层析成像、荧光成像、双光子成像、二次谐波成像等结合形成多模态的光声显微成像技术。现已在血管生物学、肿瘤学、神经学、眼科学，以及皮肤学等生物医学领域得到应用。

Cellular metabolism arouses the changes of substance in extracellular physiological microenvironment, and the metabolic level reflects the physiological state of cells. This paper developed a novel microphysiometer automatic analysis instrument based on multiparameter cell-based biosensors for quick drug analysis. This study included the multiparameter cell-based biosensors, cell culture chamber, drug auto-injection detection and analysis. The analysis instrument was capable of real-time detection for the acidic product and other chemical parameters generated by the cellular metabolism in the micro-volume. Finally, the paper employs human breast cancer cell line MCF-7 and drug experiments to verify the performance of microphysiometer, and study effects of different drugs on cell metabolism. Further, the research explores drug analysis method of the multiparameter microphysiometer. The results showed that the cell-based microphysiometer system provides a utility platform for rapid, long-term and automatic cell physiological environment detection and drug analysis.

在考虑探测光束光斑尺寸对调制光热反射(MPR)信号影响的基础上，建立了三维的薄膜-衬底体系的激光光热反射理论模型。对利用激光光热反射技术测量薄膜热物性的可行性进行了研究，并对影响调制光热反射信号的材料参数进行了分析。此外，通过数值模拟研究了多参数拟合问题，即利用调制光热反射频响信号同时确定薄膜热扩散率、衬底热扩散率和界面热阻这三个物理参数。结果表明，与已有的径向扫描方法相比，频率扫描方法中的这三个参数之间并不存在高度的相关性，因此采用频响信号进行多参数拟合，可提高多参数拟合的收敛性和精确性。

提出用椭圆纤芯高双折射光纤偏振干涉和双模干涉结合的四参量以及双模干涉的多参量同时测量的传感理论和实验原理，对交叉灵敏度作了分析，同时给出了误差分析，并结合理论模型对灵敏度矩阵的状态作了粗略估计。