羟基磷灰石超长纳米线可用于构建不同种类的生物材料, 如高柔性生物医用纸和弹性多孔骨缺损修复支架, 在生物医学领域具有良好的应用前景。锶元素作为一种微量元素, 在骨代谢过程中起着重要作用。本研究通过一步溶剂热法合成了具有不同锶掺杂量的羟基磷灰石超长纳米线; 研究了不同锶掺杂量对羟基磷灰石超长纳米线的形貌和物相的影响。所制备的锶掺杂羟基磷灰石超长纳米线具有高柔韧性和超长一维纳米结构。能量色散谱、X射线粉末衍射和傅里叶变换红外光谱分析表明, 锶元素成功地掺杂到了羟基磷灰石超长纳米线中。本研究发展的制备方法可以制备锶/(锶+钙)摩尔比从0到100%任一比例的锶掺杂羟基磷灰石超长纳米线, 大幅拓展了羟基磷灰石超长纳米线在骨缺损修复和牙科修复等生物医学领域中的应用。

Ultralong hydroxyapatite nanowires (UHANWs) exhibit great potential in constructing different kinds of biomaterials such as the highly flexible biomedical paper and elastic porous scaffolds for various biomedical applications. Moreover, strontium (Sr), a trace element in human body, plays an important role in bone metabolism. In this study, Sr-doped UHANWs (Sr-UHANWs) with various Sr/(Sr+Ca) molar ratios have been successfully prepared by the one-step oleate precursor solvothermal method. The effects of the Sr/(Sr+Ca) molar ratio on the morphology and crystal phase of the Sr-UHANWs were investigated. The as-prepared Sr-UHANWs exhibit high flexibility and ultralong 1D nanostructure. Moreover, the energy dispersive spectroscopy, X-ray powder diffraction, and Fourier transform infrared spectroscopy of the as-prepared samples reveal that Sr element has been successfully incorporated in UHANWs. The preparation method developed in this work may be suitable for the synthesis of Sr-UHANWs with Sr/(Sr+Ca) molar ratios ranging from 0 to 100 %, which may enlarge the biomedical applications of UHANWs such as bone and teeth defect repair.