表面增强拉曼散射（surface-enhanced Raman scattering,SERS）技术将纳米结构材料和拉曼光谱相结合，解决了传统拉曼散射技术灵敏度低的问题，为痕量物质检测提供了新的技术手段。高SERS活性基底材料是将拉曼光谱应用到痕量物质检测中的关键。采用磁控溅射技术结合脱合金工艺在硅片上制备出岛状纳米多孔金SERS基底，该基底的孔隙尺寸和金韧带宽度的比值远小于传统纳米多孔金，有效地增强了金韧带之间的电磁耦合效应，表现出更强的局域电磁场。该基底的检测极限可达约10⁻¹⁰ mol·L⁻¹，且SERS光谱相对强度与浓度呈现出较好的线性关系，动态响应范围可达3个数量级。同时该基底结构均匀、性能稳定，制备工艺具有良好的可重复性。

Surface-enhanced Raman scattering (SERS), which combines nanostructured materials with Raman spectroscopy, solves the problem of low sensitivity of traditional Raman scattering technique and provides a new technical means for trace detection. High SERS active substrate is the key to the application of Raman spectroscopy for trace detection. The island nanoporous gold SERS substrate was prepared by dealloying precursor alloy films which sputtered on silicon wafer, and the obtained substrate posses much smaller ratio between pore size and gold ligament size compared with traditional nanoporous gold, resulting in much stronger local electromagnetic field due to improved coupling effect between gold ligaments. The detection limit of the substrate can reach about 10^-10 mol·L^-1, and the relative intensity of SERS spectrum has a good linear relationship with the concentration, and the dynamic range can reach 3 orders of magnitude. Meanwhile, with uniform structure the substrate exhibits stable performance, and the preparation process shows good repeatability.