为了比较外阴硬化萎缩性苔藓（VLS）组织和正常外阴组织高光谱的差别，得出各自的特点和规律，本研究通过高光谱成像技术定量分析了40位VLS患者外阴皮肤组织中黑色素含量和血氧含量。实验结果表明，VLS组织中黑色素含量指数和血氧含量指数均在统计学上低于正常外阴组织。因此，通过量化正常外阴组织和VLS组织中黑色素含量指数和组织血氧饱和度指数之间的差异，高光谱成像技术为实现对VLS的在体辅助诊断提供了可能。

To compare the hyperspectral differences of the vulvar lichen sclerosis (VLS) tissue and normal vulvar tissue and extract their respective features, the melanin content and tissue oxygen saturation (StO₂) in the vulvar skin tissue of 40 patients with VLS were quantitatively analyzed via hyperspectral imaging. Our experimental results suggest that the melanin content index and StO₂ index in lesions are statistically lower than those in the normal vulvar tissues. Therefore, by quantifying the difference between melanin content index and StO₂ index in normal vulvar tissue and VLS tissue, hyperspectral imaging technology provides the possibility of in vivo assisted diagnosis of VLS.