激光与光电子学进展, 2012, 49 (2): 020001, 网络出版: 2011-11-28   

光生物调节作用研究进展 下载: 529次

Progress in Photobiomodulation Studies
作者单位
1 华南师范大学激光运动医学实验室和民族健康与体质研究中心, 广东 广州 510006
2 俄罗斯科学院激光和信息技术研究所, 俄罗斯 特罗伊次克142190
3 约翰霍普金斯大学医学院分子生物学与遗传系, 美国 马里兰州巴尔的摩 MD21205
4 鲁茨弱激光私人诊所, 德国 拜恩 94072
摘要
激光或单色光的强度可以分为低、中和高三个等级,其生物调节作用称为光生物调节作用。从内稳态的角度综述相应的研究进展。功能内稳态是维持功能充分稳定发挥的负反馈机制,它可以抵抗低于阈值的内外干扰,但被高于阈值的应激所打破。处于内稳态的应激称为成功应激,远离内稳态的应激称为慢性应激。成功应激打破一个功能内稳态之后,能够建立另一个功能内稳态。弱光可以调节慢性应激,但对成功应激或处于功能内稳态的功能无效。细胞的多种膜蛋白可以协同介导低强度单色光的自适应调节。内源性光敏剂介导中强度单色光的调节作用。弱光可以用于诊断功能内稳态或成功应激本身和其形成过程。并讨论了光生物调节作用在外科快速康复中的应用。
Abstract
Photobiomodulation (PBM) is a biomodulation of laser irradiation (LI) or monochromatic light. The LI may be low intensity LI (LIL) at about 10 mW/cm2, moderate intensity LI (MIL) at 0.1~1.0 W/cm2 or high intensity LI. The progress in PBM studies is reviewed from homeostatic viewpoint in this paper. Function-specific homeostasis (FSH) is a negative-feedback response of a biosystem to maintain the function-specific conditions inside the biosystem so that the function is perfectly performed. FSH can resist internal or/and external disturbance under threshold, but can be disrupted by FSH-specific stress (FSS). There is a FSS-specific homeostasis (FSSH) in which a FSS not only disrupts the original FSH, but also establishes a new FSH so that it is called a successful stress. Low level LI (LLL) has been so defined that it cannot modulate a successful stress or a function in its FSH, but it can modulate a FSS far from its FSSH. LIL might be coordinately mediated by many kinds of proteins in membrane of cells or cellular organellae so that the FSH can be self-adaptively established. MIL might be mediated by endogenetic photosensitive proteins. LLL can be used to diagnose the process for a function to establish its FSH or for a FSS to establish its FSSH and the FSH or FSSH itself. The applications of PBM in enhanced recovery after surgery are also discussed.
参考文献

[1] T. C. Y. Liu, L. Cheng, J. Liu et al.. Cellular traditional Chinese medicine on photobiomodulation[C]. SPIE, 2006, 6047: 60473P

[2] 刘承宜, 王艳芳, 段锐 等. 细胞光子中医学[J]. 激光与光电子学进展, 2007, 44(5): 23~29

    Liu Chengyi, Wang Yanfang, Duan Rui et al.. Cellular photonic traditional Chinese medicine[J]. Laser & Optoelectronice Progress, 2007, 44(5): 23~29

[3] T. C. Y. Liu, R. Liu, L. Zhu et al.. Homeostatic photobiomodulation[J]. Front. Optoelectron. China, 2009, 2(1): 1~8

[4] 刘承宜, 朱平. 低强度激光鼻腔内照射疗法[M]. 北京:人民军医出版社, 2009

    Liu Chengyi, Zhu Ping. Intranasal Low Intensity Laser Therapy[M]. Beijing: People′s Military Medical Press, 2009

[5] 刘承宜, 李方晖, 朱玲. 组蛋白去乙酰化酶介导的动物非视觉细胞的光康复机制[J]. 中国激光, 2009, 36(10): 2485~2492

    Liu Chengyi, Li Fanghui, Zhu Ling. Sirtuin-mediated mechanism of optical rehabiliation of non-vision animal cells[J]. Chinese J. Lasers, 2009, 36(10): 2485~2492

[6] N. Lane. Cell biology: power games[J]. Nature, 2006, 443(7114): 901~903

[7] T. Karu. The Science of Low-Power Laser Therapy[M]. Amsterdam: Gordon and Breach Science Publishers,1998

[8] W. B. Cannon. The Wisdom of the Body[M]. New York: WW Norton, 1932

[9] D. S. Jones. Textbook of Functional Medicine[M]. Gig Harbor, Wash.: The Institute for Functional Medicine, 2006

[10] I. Lestas, G. Vinnicombe, J. Paulsson. Fundamental limits on the suppression of molecular fluctuations[J]. Nature, 2010, 467(7132): 174~178

[11] 李江华, 刘承宜, 徐晓阳 等. 2006多哈亚运会短距离游泳男运动员代谢组学研究[J]. 体育科学, 2008, 28(2): 42~46

    Li Jianghua, Liu Chengyi, Xu Xiaoyang et al.. A metabonomic study on the swimming athletes participating in the short-distance competition at 15th Asian Games[J]. China Sport Science, 2008, 28(2): 42~46

[12] 梁东梅, 刘承宜, 邱丽华 等. 不同级别中国象棋运动员脑功能成像研究[J]. 体育科学, 2010, 30(8): 69~72

    Liang Dongmei, Liu Chengyi, Qiu Lihua et al.. Functional MRI studies on different level players of Chinese chess[J]. China Sport Science, 2010, 30(8): 69~72

[13] M. A. Nowak, M. C. Boerlijst, J. Cooke et al.. Evolution of genetic redundancy[J]. Nature, 1997, 388(6638): 167~171

[14] J. L. Hartman, B. Garvik, L. Hartwell. Principles for the buffering of genetic variation[J]. Science, 2001, 291(5506): 1001~1004

[15] T. C. Y. Liu, J. L. Jiao, X. Y. Xu et al.. Process Theory-The Bridge of the Eastern and Western Culture. In: M. J. Jandl, K. Greiner (eds.) Science, Medicine and Culture [M]. Frankfurt: Peter Lang GmbH, 2005. 165~175

[16] L. A. Gavrilov, N. S. Gavrilova. The reliability theory of aging and longevity[J]. Theor. Biol., 2001, 213(4): 527~545

[17] L. A. Gavrilov, N. S. Gavrilova. The quest for a general theory of aging and longevity[J]. Sci. Aging Knowledge Environ., 2003, 2003(28): RE5

[18] T. C. Y. Liu, F. H. Li. Photonic homeostatics[C]. SPIE, 2010, 7845: 78450Y

[19] M. J. Noetzel. Perinatal trauma and cerebral palsy[J]. Clin. Perinatol., 2006, 33(2): 355~366

[20] M. T. Kato, E. M. Kogawa, C. N. Santos et al.. TENS and low-level laser therapy in the management of temporomandibular disorders [J]. Appl. Oral. Sci., 2006, 14(2): 130~135

[21] M. A. Naeser, A. Saltmarche, M. H. Krengel et al.. Improved cognitive function after transcranial, light-emitting diode treatments in chronic, traumatic brain injury: two case reports[J]. Photomed·Laser Surg., 2011, 29(5): 351~358

[22] 刘振寰, 钱旭光, 马美美 等. 激光照射治疗对脑性瘫痪患儿临床微循环影响的研究[J]. 中国微循环, 2007, 11(5): 328~330

    Liu Zhenhuan, Qian Xuguang, Ma Meimei et al.. Study of clinical microcirculation effect of laser radiationon cerebral palsy[J]. J. Chinese Microcirculation, 2007, 11(5): 328~330

[23] D. A. Oliveira, R. F. De Oliveira, M. Magini et al.. Assessment of cytoskeleton and endoplasmic reticulum of fibroblast cells subjected to low-level laser therapy and low-intensity pulsed ultrasound[J]. Photomed·Laser Surg., 2009, 27(3): 461~466

[24] 杨小红, 刘承宜, 刘少杰 等. 软骨细胞光生物调节作用的体外实验[J]. 中国激光, 2006, 33(12): 1692~1698

    Yang Xiaohong, Liu Chengyi, Liu Shaojie et al.. Photobiomodulation on chondrocyte proliferation: in vitro evaluation[J]. Chinese J. Lasers, 2006, 33(12): 1692~1698

[25] X. H. Yang, T. C. Y. Liu, S. J. Liu et al.. Photobiomodulation on chondrocytes[J]. Lasers Surg·Med., 2006, 38(18S): 52

[26] T. C. Y. Liu, F. H. Li, E. X. Wei et al.. Signal transduction network mediated homeostatic photobiomodulation on high glucose induced dysfunctions of C2C12 myoblasts[J]. Mol. Biol. Cell., 2011, 22(suppl): 854

[27] 朱玲, 吴德峰, 王永庆 等. 低强度半导体激光照射调节成纤维细胞时钟基因表达[J]. 中国激光, 2011, 38(8): 0804001

    Zhu Ling, Wu Dengfeng, Wang Yongqing et al.. Modulation of low intensity laser irradiation on expression suppression of circadian clock genes in cultured fibroblasts[J]. Chinese J. Lasers, 2011, 38(8): 0804001

[28] 刘承宜, 朱平 主编. 激光功能医学及其应用[M]. 香港:精英出版社, 2012

    Liu Chengyi, Zhu Ping. Laser Function Medicine and Its Applications[M]. Hongkong: Outstanding Publication Ltd., 2012

[29] 邢达, 吴胜男. 低能量激光照射引起的细胞增殖以及凋亡效应的一些分子机制研究[J]. 激光与光电子学进展, 2009, 46(1): 19~29

    Xing Da, Wu Shengnan. Progress on molecular mechanism of biological effects induced by low-power laser irradiation[J]. Laser & Optoelectronics Progress, 2009, 46(1): 19~29

[30] 刘承宜, 朱玲, 段锐 等. 激光或单色光引起非视觉细胞信号转导的现象与机理[J]. 中国激光, 2009, 36(9): 2251~2256

    Liu Chengyi, Zhu Ling, Duan Rui et al.. Phenomena and Mechanism of laser irradiation or monochromatic light induced extraocular phototransduction[J]. Chinese J. Lasers, 2009, 36(9): 2251~2256

[31] S. Wu, D. Xing, F. Wang et al.. Mechanistic study of apoptosis induced by high-fluence low-power laser irradiation using fluorescence imaging techniques[J]. J. Biomed. Opt., 2007, 12(6): 064015

[32] J. Zhang, D. Xing, X. Gao. Low-power laser irradiation activates Src tyrosine kinase through reactive oxygen species-mediated signaling pathway[J]. Cell Physiol., 2008, 217(2): 518~528

[33] J. T. Eells, M. T. Wong-Riley, J. VerHoeve et al.. Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy[J]. Mitochondrion, 2004, 4(5-6): 559~567

[34] P. Brondon. A study of the effects of phototherapy dose interval on photobiomodulation of cell cultures[J]. Lasers Surg. Med., 2005, 36(5): 409~413

[35] T. C. Y. Liu, Y. Q. Gao, S. H. Liu. Light-cell interaction: quasi-hormone model and time theory[C]. SPIE, 1996, 2887: 140~151

[36] 刘承宜, 高云清, 刘颂豪. 关于激光对细胞生物刺激作用的类激素模型[J]. 激光杂志, 1997, 18(2): 51~53

    Liu Chengyi, Gao Yunqing, Liu Songhao. Quasi-hormone model on laser biostimulation[J]. Chinese Laser Journal, 1997, 18(2): 51~53

[37] T. C. Y. Liu, J. L. Jiao, R. Duan et al.. Membrane Mechanism of Low Intensity Laser Biostimulation on a cell. In: Z. Simunovic (ed.). Lasers in Medicine, Surgery and Dentistry[M]. Croatia: European Medical Laser Association, 2003. 83~105

[38] P. J. Campbell, P. J. Murphy. Extraocular circadian phototransduction in humans[J]. Science, 1998, 279(5349): 396~399

[39] R. Duan, T. C. Y. Liu, Y. Li et al.. Signal transduction pathway involved in low intensity He-Ne laser-induced respiratory burst in bovine neutrophils: a potential mechanism of low intensity laser biostimulation[J]. Lasers Surg. Med., 2001, 29(2): 174~178

[40] Y. Zhang, S. Song, C. C. Fong et al.. cDNA microarray analysis of gene expression profiles in human fibroblast cells irradiated with red light[J]. Invest. Dermatol., 2003, 120(5): 849~857

[41] N. Komine, K. Ikeda, K. Tada et al.. Activation of the extracellular signal-regulated kinase signal pathway by light emitting diode irradiation[J]. Lasers Med. Sci., 2010, 25(4): 531~537

[42] L. Wang, G. B. Zhou, P. Liu et al.. Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia[J]. PNAS, 2008, 105(12): 4826~4831

[43] H. Zhou, Z. Tong, J. F. McLeod. "Cocktail" approaches and strategies in drug development: valuable tool or flawed science [J]. Clin. Pharmacol., 2004, 44(2): 120~134

[44] T. C. Y. Liu, L. Luo, L. Zhang. Self-adaptive effects of low intensity laser irradiation in prophylaxis of muscular fibrosis[J]. Lasers Surg. Med., 2011, 43(S23): 975~975

[45] L. Abramovitch-Gottlib, T. Gross, D. Naveh et al.. Low level laser irradiation stimulates osteogenic phenotype of mesenchymal stem cells seeded on a three-dimensional biomatrix[J]. Lasers Med. Sci., 2005, 20(3-4): 138~146

[46] P. Gal, B. Vidinsky, T. Toporcer et al.. Histological assessment of the effect of laser irradiation on skin wound healing in rats[J]. Photomed·Laser Surg., 2006, 24(4): 480~488

[47] A. Badea, G. A. Johnson, J. L. Jankowsky. Remote sites of structural atrophy predict later amyloid formation in a mouse model of Alzheimer′s disease[J]. Neuroimage, 2010, 50(2): 416~427

[48] T. Bolmont, F. Haiss, D. Eicke et al.. Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance[J]. Neurosci., 2008, 28(16): 4283~4292

[49] M. Meyer-Luehmann, T. L. Spires-Jones, C. Prada et al.. Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer′s disease[J]. Nature, 2008, 451(7179): 720~724

[50] M. T. Wong-Riley, H. L. Liang, J. T. Eells et al.. Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase[J]. Biol. Chem., 2005, 280(6): 4761~4771

[51] F. Kamenetz, T. Tomita, H. Hsieh et al.. APP processing and synaptic function[J]. Neuron, 2003, 37(6): 925~937

[52] S. Hauptmann, I. Scherping, S. Drse et al.. Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice[J]. Neurobiol. Aging, 2009, 30(10): 1574~1586

[53] A. I. Efendiev, P. I. Tolstykh, A. I. Dadashev et al.. Increasing the scar strength after preventive skin irradiation with low-intensity laser[J]. Klin. Khir., 1992, (1): 23~25

[54] A. Derkacz, M. Protasiewicz, R. Poreba et al.. Usefulness of intravascular low-power laser illumination in preventing restenosis after percutaneous coronary intervention[J]. Am. J. Cardiol., 2010, 106(8): 1113~1117

[55] 罗丽, 刘承宜, 江毅 等. 南非足球世界杯的内稳态述评[J]. 体育学刊, 2011, 18(1): 125~132

    Luo Li, Liu Chengyi, Jiang Yi et al.. Homeostatic review on football world cup in south africa[J]. J. Physical Education, 2011, 18(1): 125~132

[56] 李方晖, 刘承宜, 伍人乐 等. 队服颜色影响体育比赛成绩的内稳态研究[J]. 体育学刊, 2008, 15(12): 96~100

    Li Fanghui, Liu Chengyi, Wu Renle et al.. Homeostatic study of the effects of team uniform colors on sports competition performance [J]. J. Physical Education, 2008, 15(12): 96~100

[57] M. P. Vizcaychipi, L. Xu, G. E. Barreto et al.. Heat shock protein 72 overexpression prevents early postoperative memory decline after orthopedic surgery under general anesthesia in mice[J]. Anesthesiology, 2011, 114(4): 891~900

[58] G. J. Wilmink, S. R. Opalenik, J. T. Beckham et al.. Molecular imaging-assisted optimization of hsp70 expression during laser-induced thermal preconditioning for wound repair enhancement[J]. Invest. Dermatol., 2009, 129(1): 205~216

[59] C. Santini. The technicoregulatory situation in France for manufactured homeopathic medications[J]. Ann. Pharm. Fr., 2005, 63(3): 212~216

[60] V. V. Pokanevych, I. L. Macheret, H. M. Chupryna et al.. The combination of reflexotherapy and homeopathy in treating patients with facial nerve neuropathy[J]. Lik. Sprava, 2000, 3(2): 115~119

[61] A. G. Guggisberg, S. M. Baumgartner, C. M. Tschopp et al.. Replication study concerning the effects of homeopathic dilutions of histamine on human basophil degranulation in vitro[J]. Complement. Ther. Med., 2005, 13(2): 91~100

[62] 刘承宜, F. A. Popp, 刘颂豪 等. 生物光子发射的半经典理论[J]. 生物物理学报, 1996, 12(3): 465~470

    Liu Chengyi, F. A. Popp, Liu Songhao et al.. Semi-classical theory on biophoton emission[J]. Acta Biophysica Sinica, 1996, 12(3): 465~470

刘承宜, 蔡庆, Karu Tiina I, 段锐, Wilden Lutz. 光生物调节作用研究进展[J]. 激光与光电子学进展, 2012, 49(2): 020001. Liu Chengyi, Cai Qing, Karu Tiina I, Duan Rui, Wilden Lutz. Progress in Photobiomodulation Studies[J]. Laser & Optoelectronics Progress, 2012, 49(2): 020001.

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