压电与声光, 2022, 44 (2): 323, 网络出版: 2022-06-14  

基于智能手机压电基片上微液滴位置分析

Sensing Position of a Droplet on a Piezoelectric Substrate Using a Smartphone
作者单位
武夷学院 微电子系,福建 武夷山 354300
摘要
为了降低微流分析成本,该文提出了基于智能手机检测压电基片上目标微液滴方法,并开发出相应的应用软件,通过分析微液滴颜色信息和几何信息定位目标微液滴位置,结合分析时间获取微液滴输运速度。为验证提出方法的正确性,以5 μL黑色墨水溶液微液滴为研究对象,进行压电基片上微液滴识别和位置分析实验。结果表明,该文所提方法和开发的应用软件可识别和定位压电基片上微液滴,在功率为27, 5 dBm时,第2~10 s段内微液滴输运速度为0, 416 mm/s。
Abstract
In order to decrease microfluidic analysis cost, a smartphone-based method for detecting the position of a droplet on piezoelectric substrate is presented, An application soft is developed for sensing droplet position, which can be obtained by analyzing its color information and geometry information, In the meantime, transportation velocity of the droplet is calculated by help of the interesting time, A 5 μL black ink solution droplet is used to demonstrate the utility of the presented method, The results show that the droplet on the piezoelectric substrate can be identified and its position can be determined using the self-developed app, The average transportation velocity of the droplet is 0, 416 mm/s from 2 s to 10 s at 27, 5 dBm of signal power,
参考文献

[1] CHEN H,POTLURI S,KOUSHANFAR F, Security of micro-fluidic biochip: Practical attacks and countermeasures[J]. ACM Transactions on Design Automation of Electronic Systems,2020,25(3):1-29,

[2] SCHWARZE J,WANKA R,ROSENHAHN A, Microfluidic accumulation assay to quantify the attachment of the marine bacterium cobetia marina on fouling-release coatings[J]. Biointerphases,2020,15(3):031014,

[3] WAHAB M A,ERDEM Y, Multi-step microfludic reactor for the synthesis of hybrid nanoparticles[J]. Journal of Micro-mechanics and Microengineering,2020,30(8):085006,

[4] SHEMBEKAR N,CHAIPAN C,UTHARALA R,et al, Droplet-based microfluidics in drug discovery,transcriptomics and high-throughput molecular genetics[J]. Lab Chip,2016,16(8):1314-1331,

[5] MONSONE A,CROSSE K M,DUAN M,et al, Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response[J]. Nature Communications,2021,12(1):4303-1-17,

[6] WANG Z,BIAN X, CHEN L, A numerical study of droplet splitting using different spacers in EWOD device[J]. Bio Chip Journal,2020,14(3):242-250,

[7] RUI X,SONG S,WANG W,et al, Applications of electrowetting-on-dielectric (EWOD) technology for droplet digital PCR[J]. Biomicrofluidics,2020,14(6):061503,

[8] MURRAN M A,NAJJARAN H, Capacitance-based droplet position estimator for digital microfluidic devices[J]. Lab on a Chip,2012,12(11):2053-2059,

[9] LI Y Y,LI H,BAKER R J, A low-cost and high-resolution droplet position detector for an intelligent electrowetting on dielectric device[J]. Journal of Laboratory Automation,2015,20(6): 663-669,

[10] SOHAIL S,BISWAS K, A novel approach for droplet position sensing in electrowetting devices[C]//Baltimore ,Maryland,USA:Proceedings of the IEEE Sensors,2013,

[11] LEI Y,HU H, SAW-driven droplet jetting technology in microfluidic:A review[J],Biomicrofluidics,2020,14(6):061505,

[12] LIM H,BACK S M,CHOI H,et al, Acoustic mixing in a dome-shaped chamber-based SAW (DC-SAW) device[J]. Lab Chip,2020,20(1):120-125,

[13] BIROUN M H,RAHMATI M,TAO R,et al, Dynamic behavior of droplet impact on inclined surfaces with acoustic waves[J]. Langmuir,2020,36/34:10175-10186,

[14] WANG S,LU X,SU Y,et al, Piezoelectric microchip for cell lysis through cell-microparticle collision within a microdroplet driven by surface acoustic wave oscillation[J]. Small,2019,15(9):e1804593,

[15] SESEN M,WHYTE G, Image-based single cell sorting automation in droplet microfluidics[J]. Scientific Reports,2020,10:8736-1-14,

[16] CHENH,ZhHENG H,LI X, Detection of multiscale center point objects based on parallel network[J]. Journal of Artificial Intelligence and Technology,2020,1(1):68-73,

[17] RENAUDIN A,SOZANSKI J P,VERBEKE B,et al, Monitoring SAW-actuated microdroplets in view of biological applications[J]. Sensors and Actuators B:Chemical,2009,138(1): 374-382,

章安良. 基于智能手机压电基片上微液滴位置分析[J]. 压电与声光, 2022, 44(2): 323. ZHANG Anliang. Sensing Position of a Droplet on a Piezoelectric Substrate Using a Smartphone[J]. Piezoelectrics & Acoustooptics, 2022, 44(2): 323.

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