心血管疾病现今已成为人类健康的头号杀手,发展高分辨的腔内影像技术有助于心血管疾病的精准诊疗。光学相干层析成像(OCT)技术具有非接触、非侵入、高分辨率且成像速度快的优点,对心血管疾病的治疗可起到关键性指导作用。首先描述了近年来中国冠脉介入手术持续增长的状况,分别介绍了OCT、内窥OCT以及心血管OCT的研究发展和应用情况,详细综述了心血管OCT在学术研究和商业转化方面的发展进程,阐述了心血管OCT在冠脉斑块临床诊断中的重要作用以及对支架手术及预后的指导性作用。最后对未来心血管OCT的发展前景作出了展望,并总结了心血管OCT的重要应用价值。

Nowadays, cardiovascular diseases have become the No. 1 killer of human health. Developing high-resolution intracavitary imaging technology is conducive to the accurate diagnosis and treatment of cardiovascular diseases. Optical coherence tomography (OCT) has the advantages of non-contact, non-invasive, high-resolution, and fast imaging capabilities, which plays a crucial role in the guidance for the treatments of cardiovascular diseases. In this work, we first described the situation of increasing cases of percutaneous coronary intervention (PCI) in China in recent years, and then the development and application of OCT, endoscopic OCT, and cardiovascular OCT were introduced. We gave a detailed review of the progress of the cardiovascular OCT in academic research and commercial translation. The importance of cardiovascular OCT in clinical diagnosis of coronary plaques and the guidance of stents and prognosis were illustrated. In the end, this article provided the prospect outlook of cardiovascular OCT in future development, and the important research and application values of cardiovascular OCT were summarized.