低强度激光治疗(LLLT)是一种通过低强度激光照射相关皮肤、穴位等人体部位治疗心脑血管疾病、缓解疼痛、促进伤口愈合的新型物理方法。它能够刺激线粒体呼吸链的复合物Ⅳ(细胞色素c氧化酶)并增加腺苷三磷酸酯、活性氧化物、一氧化氮等物质的合成, 有助于定向调节细胞行为。高血压、高血糖和高血脂(三高)是最常见的血液疾病, 其导致的血液各参数的变化将引起其他脏器功能异常。目前, “三高”的发病群体数量日益增加, 患者偏年轻化, 因此迫切需要一种便携有效的治疗技术来应对该疾病。近年来研究发现, LLLT在血液系统疾病中有明显的作用, 能有效降低高血压。此外, LLLT还可以调节血糖, 并对因血糖过高导致的相关并发症起到一定的改善, 同时还可调节血脂的浓度, 但更多的应用侧重于前两者。这种治疗技术具有无创和便携等优势, 因此有望成为新的治疗方法。本文将对有关LLLT技术在“三高”中的应用及相关的机制进行综述。

Low level laser therapy (LLLT) is a new type of physical therapy that uses low level laser to irradiate relevant skin, acupoints and other parts of the human body to treat cardiovascular and cerebrovascular diseases, relieve pain, and promote healing. It can stimulate the complex IV (cytochrome c oxidase) of the mitochondrial respiratory chain and increase the synthesis of adenosine-triphosphate, reactive oxygen species, NO and other substances, helping to regulate cell behavior in a targeted manner. The hypertension, hyperglycemia and hyperlipidemia (three highs) are the most common blood diseases. The changes in various blood parameters caused by it can easily cause other organ dysfunctions. At present, the number of “three highs” disease groups is increasing, and the patients are younger, hence, there is an urgent need for a portable and effective treatment technique to deal with the disease. In recent years, studies have found that LLLT also has a significant effect on blood system diseases and can effectively reduce high blood pressure. In addition, LLLT can also adjust blood sugar and have a certain therapeutic effect on related complications caused by high blood sugar. At the same time, it can also adjust the concentration of blood lipids, whereas more applications focus on the first two. This kind of treatment has the advantage of non-invasiveness and portability, hence, it is expected to become a new treatment method. This article will review the application of LLLT in the “three highs” and related mechanisms.