Overview: Since the groundbreaking discovery of gravitational waves, the scientific community has fervently pursued the exploration of low-frequency gravitational waves to glean deeper insights into the cosmos. The inherent limitations of ground-based conditions, however, pose formidable challenges for detectors in capturing gravitational waves below the 1 Hz threshold. Consequently, the imperative has shifted toward the deployment of space-based gravitational wave detectors as the paramount solution for effective low-frequency gravitational wave detection. At the crux of space-based gravitational wave detection lies the pivotal role of spaceborne telescopes. Given the expansive transmission distances spanning magnitudes of 10⁹ m between celestial constellations, the demand for nanoradian-level precision in telescope pointing accuracy becomes non-negotiable. The concomitant necessity for high-precision measurements and calibration emerges as a prerequisite for achieving the exacting standards of pointing accuracy in spaceborne telescopes dedicated to gravitational wave detection. To ameliorate the deleterious effects of pointing deviations on gravitational wave detection, this study strategically optimizes key parameters, including microlens structures, detector selection, and algorithmic frameworks, thereby achieving a breakthrough in high-precision pointing deviation measurements. Leveraging a low-density microlens array with extended sub-aperture focal lengths enhances the spatial scale of the light spot within each sub-aperture. This, coupled with detectors boasting a high signal-to-noise ratio, synergistically elevates the pointing detection accuracy of each discrete lens. Moreover, the paper introduces an innovative, Hartmann principle-based methodology for high-precision pointing deviation measurements, deploying a spatially reused paradigm across multiple sub-apertures. By aggregating measurement results from diverse sub-apertures, the approach effectively mitigates the influence of assorted random errors on measurement accuracy, thereby markedly enhancing the precision of pointing deviation measurements. Illustrating the efficacy of these methodologies, the paper exemplifies their application within the ambit of the "Tianqin Plan" for space-based gravitational wave detection. Employing numerical simulations and factoring in the design parameters of the Hartmann sensor, the study performs a meticulous analysis of pointing deviation measurement accuracy. Comparative analysis between single sub-aperture and sub-aperture correlation reuse technologies reveals a compelling enhancement in measurement accuracy, approximating a sevenfold improvement with the latter. The pointing deviation measurement accuracy achieved through sub-aperture correlation reuse technology is quantified at approximately 18.81 nanoradians. Considering the optical magnification inherent in spaceborne telescopes, estimated at around 30 times, the resultant pointing deviation measurement accuracy reaches an impressive 0.62 nanoradians. This design precision significantly surpasses the stipulated 1 nanoradian accuracy requirement for ground-based gravitational wave pointing deviation measurements. As a prudential measure, the proposed design incorporates a substantial margin to accommodate potential accuracy diminution attributable to external perturbations during empirical testing.

液体活检技术的兴起为黑色素瘤的快速、准确诊断提供了新的机遇。然而，普通循环肿瘤细胞活检基于上皮黏附蛋白进行阳性富集，但信号标记的有机荧光探针存在量子效率低的问题，导致检测黑色素瘤循环肿瘤细胞时准确率和灵敏度较低。本文以高量子效率的金属卤化物钙钛矿量子点作为信号标记物，以黑色素瘤来源的外泌体作为生物识别分子，构建了一种用于黑色素瘤液体活检的循环肿瘤细胞检测新策略。与商品化的上皮细胞黏附蛋白富集策略相比，本研究报道的复合探针检测新策略，其检测灵敏度提高了一个数量级，并且具有良好的亲水性和低毒性。实验结果证明了外泌体引导的金属卤化物钙钛矿量子点指示的黑色素瘤循环肿瘤细胞检测新策略具有理想的应用前景。

氮化镓作为第三代照明器件材料相较于第一代硅与第二代砷化镓在性能上有了很大提高，基于氮化镓的Micro-LED器件也愈发被人们所关注。然而由于在传统c面上生长的LED其自身所固有的一些缺陷往往在实际应用中发射效率不高，如存在量子限制斯塔克效应、绿色间隙、载流子传输等问题。基于非极性或半极性的LED没有极化电场，具有较强的内量子效率，电子和空穴复合机率大等优点，对非极性和半极性Micro-LED器件的研究与应用引起了人们很大的兴趣。本文对非极性和半极性Micro-LED器件研究现状进行综述。首先从量子限制斯托克效应、绿色间隙、载流子传输、效率下降4个方面介绍了非极性和半极性氮化镓基材料的优势。接着针对缺陷位错、增加光提取效率与在不同电流密度下实现全彩显示等问题，介绍了芯片成形、图案刻蚀与阵列这3种技术，最后对Micro-LED作为下一代显示引领者进行了展望。希望对Micro-LED今后的研究有所帮助。