低能量激光治疗(low level laser therapy, LLLT)在口腔领域应用日益广泛, 其操作相对简单、无创。研究表明, LLLT具有抗炎、减轻疼痛、加速组织愈合、生物调节等能力。有研究认为LLLT的细胞分子机制主要与线粒体的数量和活性有关, 通过提高ATP的产量, 调节细胞的新陈代谢。其中较多学者认为LLLT可加速正畸牙移动和牙槽骨的改建, 包括破骨细胞、成骨细胞数目的增加以及胶原的沉积, 加快牙移动速度, 缩短正畸疗程。深入研究LLLT在正畸牙齿移动中的应用, 具有重要的临床和科研意义。结合参考文献, 就LLLT的作用机制及其在促进正畸牙移动方面的相关研究作简要综述。

Low level laser therapy (LLLT) has been widely used in the oral field. Its operation is relatively simple and non-invasive. Studies have shown that LLLT has the ability of anti-inflammatory, relieving pain, accelerating tissue healing and biological regulation. Some studies have suggested that the cellular molecular mechanism of LLLT is mainly related to the number and activity of mitochondria. It can regulate cell metabolism by increasing ATP production. Many scholars believe that LLLT can accelerate orthodontic tooth movement and alveolar bone remodeling, including the increase of the number of osteoclasts and osteoblasts and the deposition of collagen, accelerate the speed of tooth movement and shorten the orthodontic treatment course. It is of great clinical and scientific significance to study the application of LLLT in orthodontic tooth movement. Combined with references, the mechanism of LLLT and its application in orthodontic tooth movement were reviewed.