应用激光, 2021, 41 (5): 1143, 网络出版: 2022-01-17  

低能量激光治疗促进正畸牙齿移动的研究进展

Research Progress of Low Level Laser Therapy in Promoting Orthodontic Tooth Movement
作者单位
河北医科大学口腔医学院·口腔医院, 正畸科, 河北省口腔医学重点实验室, 河北省口腔疾病临床医学研究中心,河北 石家庄 050017
摘要
低能量激光治疗(low level laser therapy, LLLT)在口腔领域应用日益广泛, 其操作相对简单、无创。研究表明, LLLT具有抗炎、减轻疼痛、加速组织愈合、生物调节等能力。有研究认为LLLT的细胞分子机制主要与线粒体的数量和活性有关, 通过提高ATP的产量, 调节细胞的新陈代谢。其中较多学者认为LLLT可加速正畸牙移动和牙槽骨的改建, 包括破骨细胞、成骨细胞数目的增加以及胶原的沉积, 加快牙移动速度, 缩短正畸疗程。深入研究LLLT在正畸牙齿移动中的应用, 具有重要的临床和科研意义。结合参考文献, 就LLLT的作用机制及其在促进正畸牙移动方面的相关研究作简要综述。
Abstract
Low level laser therapy (LLLT) has been widely used in the oral field. Its operation is relatively simple and non-invasive. Studies have shown that LLLT has the ability of anti-inflammatory, relieving pain, accelerating tissue healing and biological regulation. Some studies have suggested that the cellular molecular mechanism of LLLT is mainly related to the number and activity of mitochondria. It can regulate cell metabolism by increasing ATP production. Many scholars believe that LLLT can accelerate orthodontic tooth movement and alveolar bone remodeling, including the increase of the number of osteoclasts and osteoblasts and the deposition of collagen, accelerate the speed of tooth movement and shorten the orthodontic treatment course. It is of great clinical and scientific significance to study the application of LLLT in orthodontic tooth movement. Combined with references, the mechanism of LLLT and its application in orthodontic tooth movement were reviewed.
参考文献

[1] HUANG H C, WILLIAMS R C, KYRKANIDES S. Accelerated orthodontic tooth movement: Molecular mechanisms[J]. American Journal of Orthodontics and Dentofacial Orthopedics, 2014, 146(5): 620-632.

[2] LIMPANICHKUL W, GODFREY K, SRISUK N, et al. Effects of low-level laser therapy on the rate of orthodontic toothmovement[J]. Orthodontics & Craniofacial Research, 2006, 9(1): 38-43.

[3] RICHTER A E, ARRUDA A O, PETERS M C, et al. Incidence of caries lesions among patients treated with comprehensiveorthodontics[J]. American Journal of Orthodontics and Dentofacial Orthopedics, 2011, 139(5): 657-664.

[4] SUNKU R, ROOPESH R, KANCHERLA P, et al. Quantitative digital subtraction radiography in the assessment of external apical rootresorption induced by orthodontic therapy: a retrospective study[J]. The Journal of Contemporary Dental Practice, 2011, 12(6): 422-428.

[5] YAMASAKI K, MIURA F, SUDA T. Prostaglandin as a mediator of bone resorption induced by experimental tooth movement in rats[J]. Journal of Dental Research, 1980, 59(10): 1635-1642.

[6] TAKANO-YAMAMOTO T, KAWAKAMI M, KOBAYASHI Y, et al. The effect of local application of 1, 25-dihydroxycholecalciferol on osteoclast numbers in orthodontically treated rats[J]. Journal of Dental Research, 1992, 71(1): 53-59.

[7] SOMA S, IWAMOTO M, HIGUCHI Y, et al. Effects of continuous infusion of PTH on experimental tooth movement inrats[J]. Journal of Bone and Mineral Research, 1999, 14(4): 546-554.

[8] HASHIMOTO F, KOBAYASHI Y, MATAKI S, et al. Administration of osteocalcin accelerates orthodontic tooth movement induced by a closed coil spring in rats[J]. European Journal of Orthodontics, 2001, 23(5): 535-545.

[9] DAHHAS F Y, EL-BIALY T, AFIFY A R, et al. Effects oflow-intensity pulsed ultrasound on orthodontic tooth movement and orthodontically induced inflammatory root resorption in ovariectomized osteoporotic rats[J]. Ultrasound in Medicine & Biology, 2016, 42(3): 808-814.

[10] HAZAN-MOLINA H, AIZENBUD I, KAUFMAN H, et al. Theinfluence of shockwave therapy on orthodontic tooth movement induced in the rat[J]. Advances in Experimental Medicine and Biology, 2016, 878: 57-65.

[11] SPADARI G S, ZANIBONI E, VEDOVELLO S A S, et al. Electrical stimulation enhances tissue reorganization during orthodontic tooth movement in rats[J]. Clinical Oral Investigations, 2017, 21(1): 111-120.

[12] MAO J J, NAH H D. Growth and development: Hereditary and mechanical modulations[J]. American Journal of Orthodontics and Dentofacial Orthopedics, 2004, 125(6): 676-689.

[13] WANG L, LEE W, LEI D L, et al. Tissue responses incorticotomy and osteotomy-assisted tooth movement in the rat[J]. International Journal of Oral and Maxillofacial Surgery, 2009, 38(5): 473.

[14] DIBART S.PiezocisionTM: Accelerating orthodontic tooth movement while correcting hard and soft tissue deficiencies[J]. Frontiers of Oral Biology, 2016, 18: 102-108.

[15] ROSEN P S, FROUM S H, FROUM S J. Arationale for postsurgical laser use to effectively treat dental implants affected by peri-implantitis: two case reports[J]. The International Journal of Periodontics & Restorative Dentistry, 2020, 40(4): 561-568.

[16] ROMERO J M, VILLASANTI TORALES U A, VILLALBA MARTNEZ C J. Efficacy of laser application in dental bleaching: A randomized clinical controlled trial[J]. American Journal of Dentistry, 2020, 33(2): 79-82.

[17] SAAD I.Photobiomodulation effect of low-level laser therapy as a palliative treatment of symptomatic geographic tongue (a double-blinded randomized clinical trial)[J]. The Journal of Contemporary Dental Practice, 2020, 21(4): 453-457.

[18] REN C, MCGRATH C, GU M, et al. Low-level laser-aided orthodontic treatment of periodontally compromised patients: a randomised controlled trial[J]. Lasers in Medical Science, 2020, 35(3): 729-739.

[19] NARAYANAN R, PRABHUJI M L V, PARAMASHIVAIAH R, et al. Low-level laser therapy in combination with desensitising agent reduces dentin hypersensitivity in fluorotic and non-fluorotic teeth:A randomised, controlled, double-blind clinical trial[J]. Oral Health & Preventive Dentistry, 2019, 17(6): 547-556.

[20] 姜建华.低强度激光的临床应用与研究进展[J].浙江医学教育,2003,2(2):52-53.

[21] YAMAGUCHI M. RANK/RANKL/OPG during orthodontic toothmovement[J]. Orthodontics & Craniofacial Research, 2009, 12(2): 113-119.

[22] THEOLEYRE S, WITTRANT Y, TAT S K, et al. The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling[J]. Cytokine & Growth Factor Reviews, 2004, 15(6): 457-475.

[23] ZHU S Y, YUAN C Y, LIU Z X, et al. The mechanism of corticotomy accelerating orthodontic tooth movement in SD rats[J]. Shanghai Journal of Stomatology, 2017, 26(1): 12-16.

[24] KARU T I, PYATIBRAT L V, AFANASYEVA N I. A novel mitochondrial signaling pathway activated by visible-to-near infrared radiation[J]. Photochemistry and Photobiology, 2004, 80(2): 366-372.

[25] CARNEVALLI C M M, SOARES C P, ZNGARO R A, et al. Laser light prevents apoptosis on Cho K-1 cell line[J]. Journal of Clinical Laser Medicine & Surgery, 2003, 21(4): 193-196.

[26] OLIVEIRA D A A, DE OLIVEIRA R F, ZANGARO R A, et al. Evaluation of low-level laser therapy of osteoblastic cells[J]. Photomedicine and Laser Surgery, 2008, 26(4): 401-404.

[27] TSUKA Y, KUNIMATSU R, GUNJI H, et al. Effects of Nd: YAG low-level laser irradiation on cultured human osteoblasts migration and ATP production: in vitro study[J]. Lasers in Medical Science, 2019, 34(1): 55-60.

[28] GAO X J, XING D. Molecular mechanisms of cell proliferation induced by low power laser irradiation[J]. Journal of Biomedical Science, 2009, 16(1): 4.

[29] KARU T I, KOLYAKOV S F. Exact action spectra for cellular responses relevant to phototherapy[J]. Photomedicine and Laser Surgery, 2005, 23(4): 355-361.

[30] STEIN E, KOEHN J, SUTTER W, et al. Initial effects of low-level laser therapy on growth and differentiation of human osteoblast-like cells[J]. Wiener Klinische Wochenschrift, 2008, 120(3/4): 112-117.

[31] STEIN A, BENAYAHU D, MALTZ L, et al. Low-level laser irradiation promotes proliferation and differentiation of human osteoblasts in vitro[J]. Photomedicine and Laser Surgery, 2005, 23(2): 161-166.

[32] LAVI R, SHAINBERG A, FRIEDMANN H, et al. Low energy visible light induces reactive oxygen species generation and stimulates an increase of intracellular calcium concentration in cardiac cells[J]. Journal of Biological Chemistry, 2003, 278(42): 40917-40922.

[33] FARIAS R D, CLOSS L Q, MIGUENS S A Q, Jr. Evaluation of the use of low-level laser therapy in pain control in orthodontic patients: A randomized split-mouth clinical trial[J]. The Angle Orthodontist, 2016, 86(2): 193-198.

[34] ALBERTINI R, VILLAVERDE A B, AIMBIRE F, et al. Anti-inflammatory effects of low-level laser therapy (LLLT) with two different red wavelengths (660 nm and 684 nm) in carrageenan-induced rat paw edema[J]. Journal of Photochemistry and Photobiology B: Biology, 2007, 89(1): 50-55.

[35] CHOW R, ARMATI P, LAAKSO E L, et al. Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: a systematic review[J]. Photomedicine and Laser Surgery, 2011, 29(6): 365-381.

[36] ARTS-RIBAS M, ARNABAT-DOMINGUEZ J, PUIGDOLLERS A. Analgesic effect of a low-level laser therapy (830 nm) in early orthodontic treatment[J]. Lasers in Medical Science, 2013, 28(1): 335-341.

[37] 孙秀梅.弱激光照射减轻实验性牙移动疼痛的分子机制研究[D].长春:吉林大学,2012.

[38] XU M, DENG T T, MO F Z, et al. Low-intensity pulsed laser irradiation affects RANKL and OPG mRNA expression in rat calvarial cells[J]. Photomedicine and Laser Surgery, 2009, 27(2): 309-315.

[39] BROOKS P J, HECKLER A F, WEI K R, et al. MCSF accelerates orthodontic tooth movement by targeting preosteoclasts in mice[J]. The Angle Orthodontist, 2011, 81(2): 277-283.

[40] YAMAGUCHI M, FUJITA S, YOSHIDA T, et al. Low-energy laser irradiation stimulates the tooth movement velocity via expression of M-CSF and c-fms[J]. Orthodontic Waves, 2007, 66(4): 139-148.

[41] OZAWA Y, SHIMIZU N, KARIYA G, et al. Low-energy laser irradiation stimulates bone nodule formation at early stages of cell culture in rat calvarial cells[J]. Bone, 1998, 22(4): 347-354.

[42] CIFTER M, CELIKEL A D G, CIFTER E D, et al. Comparison of the efficiency of alveolar decortication and low level laser therapy on orthodontic tooth movement and alveolar metabolism in rats[J]. Journal of Dental Sciences, 2019, 14(4): 401-407.

[43] KAWASAKI K, SHIMIZU N. Effects of low-energy laser irradiation on bone remodeling during experimental tooth movement in rats[J]. Lasers in Surgery and Medicine, 2000, 26(3): 282-291.

[44] FIGUEIRA I Z, SOUSA A P C, MACHADO A W, et al. Clinical study on the efficacy of LED phototherapy for pain control in an orthodontic procedure[J]. Lasers in Medical Science, 2019, 34(3): 479-485.

[45] MARINI I, BARTOLUCCI M L, BORTOLOTTI F, et al. The effect of diode superpulsed low-level laser therapy on experimental orthodontic pain caused by elastomeric separators: A randomized controlled clinical trial[J]. Lasers in Medical Science, 2015, 30(1): 35-41.

[46] WU S, CHEN Y N, ZHANG J L, et al. Effect of low-level laser therapy on tooth-related pain and somatosensory function evoked by orthodontic treatment[J]. International Journal of Oral Science, 2018(3):182-189.

[47] QAMRUDDIN I, ALAM M K, ABDULLAH H, et al. Effects of single-dose, low-level laser therapy on pain associated with the initial stage of fixed orthodontic treatment: a randomized clinical trial[J]. Korean Journal of Orthodontics, 2018, 48(2): 90-97.

[48] ALMALLAH M M E, HAJEER M Y, ALMAHDI W H, et al. Assessment of a single versus double application of low-level laser therapy in pain reduction following orthodontic elastomeric separation: A randomized controlled trial[J]. Dental and Medical Problems, 2020, 57(1): 45-52.

[49] 陈荟忆,袁小平.弱激光照射减轻正畸疼痛的研究进展[J].西南军医,2014,16(1):64-67.

[50] VERSCHUEREN R C, KOUDSTAAL J, OLDHOFF J. The carbon dioxide laser; some possibilities in surgery[J]. Acta Chirurgica Belgica, 1975, 74(2): 197-204.

[51] VARELLA A M, REVANKAR A V, PATIL A K. Low-level laser therapy increases interleukin-1β in gingival crevicular fluid and enhances the rate of orthodontic tooth movement[J]. American Journal of Orthodontics and Dentofacial Orthopedics, 2018, 154(4): 535-544.e5.

[52] KOCHAR G D, LONDHE S M, VARGHESE B, et al. Effect of low-level laser therapy on orthodontic tooth movement[J]. Journal of Indian Orthodontic Society, 2017, 51(2): 81-86.

[53] ALSAYED HASAN M M A, SULTAN K, HAMADAH O. Low-level laser therapy effectiveness in accelerating orthodontic tooth movement: A randomized controlled clinical trial[J]. The Angle Orthodontist, 2017, 87(4): 499-504.

[54] DA SILVA SOUSA M V, SCANAVINI M A, SANNOMIYA E K, et al. Influence of low-level laser on the speed of orthodontic movement[J]. Photomedicine and Laser Surgery, 2011, 29(3): 191-196.

[55] GURAM G, REDDY R K, DHARAMSI A M, et al. Evaluation of low-level laser therapy on orthodontic tooth movement: A randomized control study[J]. Contemporary Clinical Dentistry, 2018, 9(1): 105-109.

[56] DALAIE K, HAMEDI R, KHARAZIFARD M J, et al. Effect of low-level laser therapy on orthodontic tooth movement: A clinical investigation[J]. Journal of Dentistry, 2015, 12(4): 249-256.

[57] MISTRY D, DALCI O, PAPAGEORGIOU S N, et al. The effects of a clinically feasible application of low-level laser therapy on the rate of orthodontic tooth movement: A triple-blind, split-mouth, randomized controlled trial[J]. American Journal of Orthodontics and Dentofacial Orthopedics, 2020, 157(4): 444-453.

[58] CHUNG S E V, TOMPSON B, GONG S G. The effect of light emitting diode phototherapy on rate of orthodontic tooth movement: A split mouth, controlled clinical trial[J]. Journal of Orthodontics, 2015, 42(4): 274-283.

[59] FINI M B, OLYAEE P, HOMAYOUNI A. The effect of low-level laser therapy on the acceleration of orthodontic tooth movement[J]. Journal of Lasers in Medical Sciences, 2020, 11(2): 204-211.

常维维, 马文盛. 低能量激光治疗促进正畸牙齿移动的研究进展[J]. 应用激光, 2021, 41(5): 1143. Chang Weiwei, Ma Wensheng. Research Progress of Low Level Laser Therapy in Promoting Orthodontic Tooth Movement[J]. APPLIED LASER, 2021, 41(5): 1143.

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